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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
 

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Article DOI: 10.3791/51504-v • 06:34 min • June 20th, 2014
June 20th, 2014 •
1, 1
1Max-Planck-Institut fuer Kohlenforschung

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résumé
Automatic Translation

A two-step procedure for the synthesis of pharmaceutically active indole-derivatives by C-H functionalization with anilines is described, using photo- and Brønsted acid catalysis.

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C-H Functionalization Tetrahydrocarbazole Derivatives Photochemical Synthesis Acid-catalyzed Synthesis Antiviral Compounds Intermediate Peroxides (CHIPS) Green Chemistry Oxidative Coupling Reactions Elemental Oxygen As Oxidant Hydroperoxide Generation N-nucleophile Introduction Brønsted-acid Catalysis Biologically Active Compound Synthesis
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