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Immunology and Infection

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JoVE Journal Immunology and Infection
Organoids as Model for Infectious Diseases
 

Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori

Article DOI: 10.3791/53359-v • 10:30 min • November 12th, 2015
November 12th, 2015 •
1, 1
1Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Centre Utrecht

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résumé
Automatic Translation

Stem cell derived cultures harbor tremendous potential to model infectious diseases. Here, the culture of mouse and human gastric organoids derived from adult stem cells is described. The organoids are microinjected with the gastric pathogen Helicobacter pylori.

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Keywords: Organoids Gastric Organoids Helicobacter Pylori Host-pathogen Interactions Stem Cells Infectious Diseases Culture Microinjection Imaging
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