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Preparing a 68Ga-labeled Arginine Glycine Aspartate (RGD)-peptide for Angiogenesis
 

Preparing a 68Ga-labeled Arginine Glycine Aspartate (RGD)-peptide for Angiogenesis

Article DOI: 10.3791/58218-v • 07:48 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1, 1, 1, 1
1Division of Applied RI, Korea Institute of Radiological and Medical Sciences

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The αvβ3 integrin is a type of adhesion protein that is highly expressed on activated endothelial cells undergoing angiogenesis. Thus, evaluating the integrity of the integrin is of great interest in oncology. Here, we introduce a method to prepare 68Ga-labeled radiopeptides and a method to assess its biological effectiveness.

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Keywords: 68Ga-labeled RGD-peptide Radiolabeling HPLC Purification ITLC In Vitro Cell Uptake Serum Stability
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