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Metionin Funksjonalisert biokompatible Block Kopolymerer for målrettet plasmider DNA levering
 
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Metionin Funksjonalisert biokompatible Block Kopolymerer for målrettet plasmider DNA levering

Article DOI: 10.3791/58527-v • 08:09 min • August 6th, 2019
August 6th, 2019 •
*1, *2, 2, 3, 2, 3, 1, 2
1Research Center of Clinical Oncology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, 2Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, 3School of Clinical Medicine, Xuzhou Medical University
* These authors contributed equally

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Dette arbeidet presenterer utarbeidelse av metionin funksjonalisert biokompatible Block kopolymerer (mBG) via reversibel tillegg fragmentering kjeden Transfer (RAFT) metoden. Plasmider DNA-kompleks evne til den oppnådde mBG og deres transfeksjoner effektivitet ble også undersøkt. FLÅTEN metoden er svært gunstig for lysherde monomerer inneholder spesielle funksjonelle grupper.

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Kjemi reversibel tillegg-fragmentering kjede overføring RAFT medikament leveringssystem DDS metionin guaniniumtiocyanat n-(3-aminopropyl) methacrylamide HYDROCHLORIDE APMA n,n-BIS(2-hydroxyethyl) methacrylamide BNHEMA
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