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A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
 

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation

Article DOI: 10.3791/59197-v • 09:12 min • April 27th, 2019
April 27th, 2019 •
1,2, 1, 1, 1,2, 1, 3, 1, 4,5, 1,6, 1,2,6
1Division of Cardiovascular Surgery, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, 2Institute of Medical Science, University of Toronto, 3Perfusion and Anesthesia Services, Toronto General Hospital, University Health Network, 4Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, 5Department of Anesthesia, University of Toronto, 6Department of Surgery, Faculty of Medicine, University of Toronto

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Automatic Translation

Here, we describe a pre-clinical large-animal (porcine) model of orthotopic heart transplantation that has been firmly established and utilized to investigate novel cardioprotective strategies.

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Pre-clinical Porcine Model Orthotopic Heart Transplantation Heart Preservation Strategies Large-animal Model Clinical Translation Porcine Heart Model Anatomy Physiology Size Research Cardiac Surgery Pericardium Donor Pig Right Ventricular Outflow Tract Pulmonary Artery Aorta Lesions Cautery Aortal Pulmonary Space Connective Tissue 4.0 PROLENE Suture Purse String Stitch Tourniquet Cardioplegia Delivery Cannula Ascending Aorta Left Inferior Pulmonary Vein Superior Vena Cavae Inferior Vena Cavae Cardiac Venting
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