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Cancer Research

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JoVE Journal Cancer Research
Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
 

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

Article DOI: 10.3791/60687-v • 10:32 min • December 19th, 2019
December 19th, 2019 •
1, 2, 1
1Department of Molecular and Cellular Physiology, Albany Medical College, 2Department of Neuroscience and Experimental Therapeutics, Albany Medical College

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The described approach combines experimental tail vein metastasis assays with in vivo live animal imaging to allow real-time monitoring of breast cancer metastasis formation and growth in addition to the quantification of metastasis number and size in the lungs.

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Keywords: Tail Vein Metastasis Assay Real-time In Vivo Imaging Breast Cancer Metastatic Colonization Metastasis Burden Lung T1 Cells Luciferase Fluorescent Protein Viral Transduction Cell Culture Cell Counting Cell Injection Animal Model
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