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Immunology and Infection

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JoVE Journal Immunology and Infection
建立猪外维沃角膜模型研究药物治疗细菌性角膜炎
 
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建立猪外维沃角膜模型研究药物治疗细菌性角膜炎

Article DOI: 10.3791/61156-v • 09:22 min • May 12th, 2020
May 12th, 2020 •
1,2, 3, 4, 1,5, 3, 1,6, 1,7, 1,2
1Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms (SCARAB), University of Sheffield, 2Department of Chemical and Biological Engineering, University of Sheffield, 3Hyderabad Eye Research Foundation, L V Prasad Eye Institute, 4Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, 5Department of Molecular Biology and Biotechnology, University of Sheffield, 6Department of Materials Science and Engineering, University of Sheffield, 7Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield

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本文描述了建立细菌性角膜炎前活体猪模型的分步协议。 伪多莫纳斯阿鲁吉诺萨 被用作原型生物体。这种创新模式模仿体内感染，因为细菌的增殖取决于细菌破坏角膜组织的能力。

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免疫学和感染， 第 159 期， 伪多莫纳斯 · 阿鲁吉诺萨， 角膜炎， 角膜， 前体内， 眼睛， 猪
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