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JoVE Journal Neuroscience
Semi-kvantitativ bestemmelse af dopaminergisk neurontæthed i Substantia Nigra af gnavermodeller ved hjælp af automatiseret billedanalyse
 
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Semi-kvantitativ bestemmelse af dopaminergisk neurontæthed i Substantia Nigra af gnavermodeller ved hjælp af automatiseret billedanalyse

Article DOI: 10.3791/62062-v • 06:09 min • February 2nd, 2021
February 2nd, 2021 •
1,2, 1,2, 1,2, 1,2,3, 1,2,4,5,6
1Krembil Research Institute, Toronto Western Hospital, University Health Network, 2Department of Laboratory Medicine and Pathobiology, University of Toronto, 3Department of Surgery, Division of Neurosurgery, University of Toronto, 4Department of Medicine, Division of Neurology, University of Toronto, 5Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, 6Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto

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Her præsenterer vi en automatiseret metode til semi-kvantitativ bestemmelse af dopaminergisk neuron nummer i rotte substantia nigra pars compacta.

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Neurovidenskab Problem 168 alfasynuclein billedprotantitation neurodegeneration Parkinsons sygdom stereologi
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