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A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
 

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Article DOI: 10.3791/62846-v • 06:58 min • July 12th, 2021
July 12th, 2021 •
1, 2, 1
1Department of Developmental and Cell Biology, University of California, 2Department of Anatomy and Neurobiology, University of California

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The goal of the method is to screen for hyperthermia or heat-induced seizures in mouse models. The protocol describes the use of a custom-built chamber with continuous monitoring of the body temperature to determine whether elevated body temperature leads to seizures.

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Behavioral Screen Heat-induced Seizures Mouse Models Of Epilepsy GEFS+ Mutations Febrile Seizures Hypothermia Induced Seizures Specific Mutations Seizure Profile Digital Temperature Controller Heating Box Reproducible Manner Mouse Body Temperature Potential Therapies Drugs Dietary Restrictions Reduce Febrile Seizures Rectal Temperature Probe Mouse Heat Chamber Power On Button Heat On Button Digital Temperature Controller Cob Bedding Video Recording Camera Cooling Pad Screening Assay Body Weight Of The Mouse
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