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A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model
 

A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model

Article DOI: 10.3791/64418-v • 08:24 min • November 25th, 2022
November 25th, 2022 •
1, 1, 1
1Department of Biological Sciences, Ajou University

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An in vivo physiological model of α-synuclein is required to study and understand the pathogenesis of Parkinson's disease. We describe a method to monitor the cytotoxicity and aggregate formation of α-synuclein using a humanized yeast model.

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Keywords: α-synuclein Yeast Model Parkinson's Disease Protein Aggregation Cellular Phenotypes Genetic Factors Growth Assay Toxicity
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