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JoVE Journal Neuroscience
Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method
 

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method

Article DOI: 10.3791/62118-v • 08:07 min • July 4th, 2021
July 4th, 2021 •
*1, *2, *3, 4, 5, 6,7, 8
1Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 2Rehabilitation Department, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, 3Department of Neurosurgery, the Hospital of Changle, 4Pediatrics Ward 2, Shouguang Hospital of Traditional Chinese Medicine, 5Fujian University of Traditional Chinese Medicine, 6National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, 7Rehabilitation Industry Institute, Fujian University of Traditional Chinese Medicine, 8Department of Neurosurgery, the First Affiliated Hospital of Wenzhou Medical University
* These authors contributed equally

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Here, we establish a novel Sprague-Dawley (SD) rat model of superior sagittal sinus (SSS) thrombosis via a thread-embolization method, and the stability and reliability of the model were verified.

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Rat Model Superior Sagittal-sinus Occlusion Thread-embolism Method CVST Study SD-Rat CVST Model Self-made Thread-embolization Stereotaxic Frame Anesthetic Injection Gel Ophthalmic Eye Lubricant Hair Removal Povidone Iodine Sterilization Skin Incision Fascia Cutting Periosteum Peeling Skull Exposure Anterior Fontanelle Posterior Fontanelle Blood Flow Observational Area Laser-speckle Blood Flow Imaging
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