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Bioengineering

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JoVE Journal Bioengineering
Ett mikrofysiologiskt system för att studera leukocyt-endotelcellinteraktion under inflammation
 
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Ett mikrofysiologiskt system för att studera leukocyt-endotelcellinteraktion under inflammation

Article DOI: 10.3791/63312-v • 12:55 min • December 9th, 2021
December 9th, 2021 •
1, 2, 3, 4, 5, 1,2,6
1Department of Mechanical Engineering, Temple University, 2Department of Bioengineering, Temple University, 3Department of Bioengineering, University of Toledo, 4Biomedical Technology, CFD Research Corporation, 5Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University, 6Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University

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I detta protokoll används en biomimetisk mikrofluidanalys, som kan reproducera en fysiologiskt relevant mikrovaskulär miljö och reproducera hela leukocytvidhäftningen / migrationskaskaden, för att studera leukocyt-endotelcellinteraktioner vid inflammatorisk sjukdom.

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Bioengineering utgåva 178 mikrofysiologiskt system leukocyt-endotelcellinteraktion inflammation vidhäftning migration biomimetisk mikrofluidanalys
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