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Bioengineering

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JoVE Journal Bioengineering
Et mikrofysiologisk system for å studere leukocytt-endotelial celleinteraksjon under betennelse
 
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Et mikrofysiologisk system for å studere leukocytt-endotelial celleinteraksjon under betennelse

Article DOI: 10.3791/63312-v • 12:55 min • December 9th, 2021
December 9th, 2021 •
1, 2, 3, 4, 5, 1,2,6
1Department of Mechanical Engineering, Temple University, 2Department of Bioengineering, Temple University, 3Department of Bioengineering, University of Toledo, 4Biomedical Technology, CFD Research Corporation, 5Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University, 6Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University

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I denne protokollen brukes en biomimetisk mikrofluidanalyse, som kan reprodusere et fysiologisk relevant mikrovaskulært miljø og reprodusere hele leukocyttadhesjons-/migrasjonskaskaden, til å studere leukocytt-endoteliale celleinteraksjoner ved inflammatorisk sykdom.

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Bioengineering Utgave 178 mikrofysiologisk system leukocytt-endotelial celleinteraksjon betennelse vedheft migrasjon biomimetisk mikrofluidanalyse
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