Alexander Fish Oncode Institute and Division of Biochemistry the Netherlands Cancer Institute Biography Publications Institution JoVE Articles Alexander Fish has not added a biography. If you are Alexander Fish and would like to personalize this page please email our Author Liaison for assistance. Publications A Fragment-like Approach to PYCR1 Inhibition Bioorganic & Medicinal Chemistry Letters. 09, 2019 | Pubmed ID: 31362921 LNA Modification of Single-stranded DNA Oligonucleotides Allows Subtle Gene Modification in Mismatch-repair-proficient Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 26951689 Cohesin Releases DNA Through Asymmetric ATPase-Driven Ring Opening Molecular Cell. Feb, 2016 | Pubmed ID: 26895426 Hoefavidin: A Dimeric Bacterial Avidin with a C-terminal Binding Tail Journal of Structural Biology. Aug, 2015 | Pubmed ID: 26126731 Late Endosomal Transport and Tethering Are Coupled Processes Controlled by RILP and the Cholesterol Sensor ORP1L Journal of Cell Science. Aug, 2013 | Pubmed ID: 23729732 Ubiquitin-specific Protease 4 is Inhibited by Its Ubiquitin-like Domain EMBO Reports. Apr, 2011 | Pubmed ID: 21415856 Structure of the HECT:ubiquitin Complex and Its Role in Ubiquitin Chain Elongation EMBO Reports. Apr, 2011 | Pubmed ID: 21399620 Nonhydrolyzable Ubiquitin-isopeptide Isosteres As Deubiquitinating Enzyme Probes Journal of the American Chemical Society. Jul, 2010 | Pubmed ID: 20540574 Venezuelan Equine Encephalitis Virus Capsid Protein Forms a Tetrameric Complex with CRM1 and Importin Alpha/beta That Obstructs Nuclear Pore Complex Function Journal of Virology. May, 2010 | Pubmed ID: 20147401 Ubc9 Sumoylation Regulates SUMO Target Discrimination Molecular Cell. Aug, 2008 | Pubmed ID: 18691969 A Supraphysiological Nuclear Export Signal is Required for Parvovirus Nuclear Export Molecular Biology of the Cell. Jun, 2008 | Pubmed ID: 18385513 Homodimerization Antagonizes Nuclear Export of Survivin Traffic (Copenhagen, Denmark). Nov, 2007 | Pubmed ID: 17714426 Dual Role of MutS Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair The EMBO Journal. Jan, 2006 | Pubmed ID: 16407973 Dynamic Kinetochore Size Regulation Promotes Microtubule Capture and Chromosome Biorientation in Mitosis Nature Cell Biology. | Pubmed ID: 29915359 The Structure of the GemC1 Coiled Coil and Its Interaction with the Geminin Family of Coiled-coil Proteins Acta Crystallographica. Section D, Biological Crystallography. | Pubmed ID: 26527144 The Polybasic Insertion in Autotaxin α Confers Specific Binding to Heparin and Cell Surface Heparan Sulfate Proteoglycans The Journal of Biological Chemistry. | Pubmed ID: 23150666 Binding of the J-binding Protein to DNA Containing Glucosylated HmU (base J) or 5-hmC: Evidence for a Rapid Conformational Change Upon DNA Binding Journal of the American Chemical Society. | Pubmed ID: 22775585 Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery Misbha Ud Din Ahmad1, Alexander Fish1, Jeroen Molenaar1, Sridhar Sreeramulu2, Christian Richter2, Nadide Altincekic2, Harald Schwalbe2, Hans Wienk1, Anastassis Perrakis1 1Oncode Institute and Division of Biochemistry, the Netherlands Cancer Institute, 2Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University JoVE 62469 생화학
Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery Misbha Ud Din Ahmad1, Alexander Fish1, Jeroen Molenaar1, Sridhar Sreeramulu2, Christian Richter2, Nadide Altincekic2, Harald Schwalbe2, Hans Wienk1, Anastassis Perrakis1 1Oncode Institute and Division of Biochemistry, the Netherlands Cancer Institute, 2Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University JoVE 62469 생화학