Sridhar Sreeramulu Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ) Johann Wolfgang Goethe-University Biography Publications Institution JoVE Articles Sridhar Sreeramulu has not added a biography. If you are Sridhar Sreeramulu and would like to personalize this page please email our Author Liaison for assistance. Publications H,C and N Chemical Shift Assignments of the SUD Domains of SARS-CoV-2 Non-structural Protein 3c: "The SUD-M and SUD-C Domains" Biomolecular NMR Assignments. 04, 2021 | Pubmed ID: 33423172 H,C and N Chemical Shift Assignments of the SUD Domains of SARS-CoV-2 Non-structural Protein 3c: "the N-terminal Domain-SUD-N" Biomolecular NMR Assignments. 04, 2021 | Pubmed ID: 33225414 F NMR-Based Fragment Screening for 14 Different Biologically Active RNAs and 10 DNA and Protein Counter-Screens Chembiochem : a European Journal of Chemical Biology. Jan, 2021 | Pubmed ID: 32794266 Secondary Structure Determination of Conserved SARS-CoV-2 RNA Elements by NMR Spectroscopy Nucleic Acids Research. 12, 2020 | Pubmed ID: 33167030 NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity Toward the EPHrin Family ChemMedChem. 08, 2018 | Pubmed ID: 29928781 Modulation of the Allosteric Communication Between the Polo-Box Domain and the Catalytic Domain in Plk1 by Small Compounds ACS Chemical Biology. 08, 2018 | Pubmed ID: 29927572 Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors ChemMedChem. 06, 2017 | Pubmed ID: 28544567 Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs ACS Chemical Biology. 12, 2016 | Pubmed ID: 27768280 Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells ACS Chemical Biology. Nov, 2015 | Pubmed ID: 26279064 High-resolution Crystal Structure of CAMP-dependent Protein Kinase from Cricetulus Griseus Acta Crystallographica. Section F, Structural Biology Communications. Aug, 2015 | Pubmed ID: 26249705 Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating During Senescence of Podospora Anserina The Journal of Biological Chemistry. Jun, 2015 | Pubmed ID: 25979334 MOTOR: Model Assisted Software for NMR Structure Determination Proteins. Nov, 2013 | Pubmed ID: 23852655 The Apo-structure of the Low Molecular Weight Protein-tyrosine Phosphatase A (MptpA) from Mycobacterium Tuberculosis Allows for Better Target-specific Drug Development The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22888002 Influence of Heparin Mimetics on Assembly of the FGF.FGFR4 Signaling Complex The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20547770 Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90-Cdc37, a Kinome Chaperone-cochaperone, by Triterpene Celastrol Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19585625 The Human Cdc37.Hsp90 Complex Studied by Heteronuclear NMR Spectroscopy The Journal of Biological Chemistry. Feb, 2009 | Pubmed ID: 19073599 Folding and Activity of CAMP-dependent Protein Kinase Mutants FEBS Letters. Aug, 2005 | Pubmed ID: 16026785 Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery Misbha Ud Din Ahmad1, Alexander Fish1, Jeroen Molenaar1, Sridhar Sreeramulu2, Christian Richter2, Nadide Altincekic2, Harald Schwalbe2, Hans Wienk1, Anastassis Perrakis1 1Oncode Institute and Division of Biochemistry, the Netherlands Cancer Institute, 2Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University JoVE 62469 생화학
Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery Misbha Ud Din Ahmad1, Alexander Fish1, Jeroen Molenaar1, Sridhar Sreeramulu2, Christian Richter2, Nadide Altincekic2, Harald Schwalbe2, Hans Wienk1, Anastassis Perrakis1 1Oncode Institute and Division of Biochemistry, the Netherlands Cancer Institute, 2Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University JoVE 62469 생화학