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JoVE Journal Medicine
Oprichting van een Human Multiple Myeloma Xenograft Model in de Chicken tumorgroei, invasie en Angiogenese Studie
 
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Oprichting van een Human Multiple Myeloma Xenograft Model in de Chicken tumorgroei, invasie en Angiogenese Studie

Article DOI: 10.3791/52665-v • 10:04 min • May 1st, 2015
May 1st, 2015 •
*1,4, *1,2, 1, 1,3
1Department of Internal Medicine V, Innsbruck Medical University, 2Oncotyrol GmbH, 3Tyrolean Cancer Research Institute, 4Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute
* These authors contributed equally

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Human multiple myeloma (MM) cellen vereisen ondersteunende micromilieu van mesenchymale cellen en extracellulaire matrix componenten voor overleving en proliferatie. Wij vestigden een in vivo model van kippenembryo engrafted humane myeloma en mesenchymale cellen effecten van kanker geneesmiddelen op tumorgroei, invasie en angiogenese.

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Geneeskunde CAM angiogenese mesenchymale cellen multipel myeloom GFP 3- dimensionale weefselkweek xenotransplantaten tumor
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