Angelo C. Lepore Department of Neuroscience, Farber Institute for Neurosciences Sidney Kimmel Medical College at Thomas Jefferson University Biography Publications Institution JoVE Articles Angelo C. Lepore has not added a biography. If you are Angelo C. Lepore and would like to personalize this page please email our Author Liaison for assistance. Publications GLT1 Overexpression in SOD1(G93A) Mouse Cervical Spinal Cord Does Not Preserve Diaphragm Function or Extend Disease Neurobiology of Disease. Jun, 2015 | Pubmed ID: 25818008 Transplantation of Stem Cell-derived Astrocytes for the Treatment of Amyotrophic Lateral Sclerosis and Spinal Cord Injury World Journal of Stem Cells. Mar, 2015 | Pubmed ID: 25815122 Dysregulation of Kv3.4 Channels in Dorsal Root Ganglia Following Spinal Cord Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2015 | Pubmed ID: 25609640 Transplantation of Glial Progenitors That Overexpress Glutamate Transporter GLT1 Preserves Diaphragm Function Following Cervical SCI Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2015 | Pubmed ID: 25492561 Inhibiting Drug Efflux Transporters Improves Efficacy of ALS Therapeutics Annals of Clinical and Translational Neurology. Dec, 2014 | Pubmed ID: 25574474 Persistent At-level Thermal Hyperalgesia and Tactile Allodynia Accompany Chronic Neuronal and Astrocyte Activation in Superficial Dorsal Horn Following Mouse Cervical Contusion Spinal Cord Injury PloS One. 2014 | Pubmed ID: 25268642 Therapeutically Targeting Astrocytes with Stem and Progenitor Cell Transplantation Following Traumatic Spinal Cord Injury Brain Research. Sep, 2014 | Pubmed ID: 25251595 Immunohistochemical Toolkit for Tracking and Quantifying Xenotransplanted Human Stem Cells Regenerative Medicine. 2014 | Pubmed ID: 25159062 Overexpression of the Astrocyte Glutamate Transporter GLT1 Exacerbates Phrenic Motor Neuron Degeneration, Diaphragm Compromise, and Forelimb Motor Dysfunction Following Cervical Contusion Spinal Cord Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2014 | Pubmed ID: 24872566 Chronic At-level Thermal Hyperalgesia Following Rat Cervical Contusion Spinal Cord Injury is Accompanied by Neuronal and Astrocyte Activation and Loss of the Astrocyte Glutamate Transporter, GLT1, in Superficial Dorsal Horn Brain Research. Sep, 2014 | Pubmed ID: 24833066 Early Phrenic Motor Neuron Loss and Transient Respiratory Abnormalities After Unilateral Cervical Spinal Cord Contusion Journal of Neurotrauma. Jun, 2013 | Pubmed ID: 23534670 Degeneration of Phrenic Motor Neurons Induces Long-term Diaphragm Deficits Following Mid-cervical Spinal Contusion in Mice Journal of Neurotrauma. Dec, 2012 | Pubmed ID: 23176637 Phrenic Motor Neuron Degeneration Compromises Phrenic Axonal Circuitry and Diaphragm Activity in a Unilateral Cervical Contusion Model of Spinal Cord Injury Experimental Neurology. Jun, 2012 | Pubmed ID: 22465264 Human Glial-restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1 Mouse Model of ALS PloS One. 2011 | Pubmed ID: 21998733 Astrocytes Carrying the Superoxide Dismutase 1 (SOD1G93A) Mutation Induce Wild-type Motor Neuron Degeneration in Vivo Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21969586 Stem Cell Transplantation for Spinal Cord Neurodegeneration Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21913120 Reduction in Expression of the Astrocyte Glutamate Transporter, GLT1, Worsens Functional and Histological Outcomes Following Traumatic Spinal Cord Injury Glia. Aug, 2011 | Pubmed ID: 21882244 Spatial and Temporal Changes in Promoter Activity of the Astrocyte Glutamate Transporter GLT1 Following Traumatic Spinal Cord Injury Journal of Neuroscience Research. Jul, 2011 | Pubmed ID: 21488085 Peripheral Hyperstimulation Alters Site of Disease Onset and Course in SOD1 Rats Neurobiology of Disease. Sep, 2010 | Pubmed ID: 20381620 Focal Transplantation-based Astrocyte Replacement is Neuroprotective in a Model of Motor Neuron Disease Nature Neuroscience. Nov, 2008 | Pubmed ID: 18931666 Selective Ablation of Proliferating Astrocytes Does Not Affect Disease Outcome in Either Acute or Chronic Models of Motor Neuron Degeneration Experimental Neurology. Jun, 2008 | Pubmed ID: 18410928 Adult Glial Precursor Proliferation in Mutant SOD1G93A Mice Glia. Jan, 2008 | Pubmed ID: 18023016 Intraparenchymal Spinal Cord Delivery of Adeno-associated Virus IGF-1 is Protective in the SOD1G93A Model of ALS Brain Research. Dec, 2007 | Pubmed ID: 17963733 Transplantation of Neuronal and Glial Restricted Precursors into Contused Spinal Cord Improves Bladder and Motor Functions, Decreases Thermal Hypersensitivity, and Modifies Intraspinal Circuitry The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2005 | Pubmed ID: 16237167 Neural Precursor Cells Can Be Delivered into the Injured Cervical Spinal Cord by Intrathecal Injection at the Lumbar Cord Brain Research. May, 2005 | Pubmed ID: 15910779 Differential Fate of Multipotent and Lineage-restricted Neural Precursors Following Transplantation into the Adult CNS Neuron Glia Biology. May, 2004 | Pubmed ID: 16520830 Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons Melanie Martin1,2, Ke Li1, Megan C. Wright2, Angelo C. Lepore1 1Department of Neuroscience, Farber Institute for Neurosciences, Sidney Kimmel Medical College at Thomas Jefferson University, 2Department of Biology, Arcadia University JoVE 52605 Neurociência Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury Angelo C. Lepore1 1Department of Neuroscience, Thomas Jefferson University Medical College JoVE 3069 Medicina
Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons Melanie Martin1,2, Ke Li1, Megan C. Wright2, Angelo C. Lepore1 1Department of Neuroscience, Farber Institute for Neurosciences, Sidney Kimmel Medical College at Thomas Jefferson University, 2Department of Biology, Arcadia University JoVE 52605 Neurociência
Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury Angelo C. Lepore1 1Department of Neuroscience, Thomas Jefferson University Medical College JoVE 3069 Medicina