Chang-Shi Chen Institute of Basic Medical Sciences, College of Medicine National Cheng Kung University Biography Publications Institution JoVE Articles Chang-Shi Chen has not added a biography. If you are Chang-Shi Chen and would like to personalize this page please email our Author Liaison for assistance. Publications Rationally Designed Divalent Caffeic Amides Inhibit Amyloid-β Fibrillization, Induce Fibril Dissociation, and Ameliorate Cytotoxicity European Journal of Medicinal Chemistry. Oct, 2018 | Pubmed ID: 30227353 RIOK-1 Is a Suppressor of the P38 MAPK Innate Immune Pathway in Frontiers in Immunology. 2018 | Pubmed ID: 29719537 A Multi-omic Analysis Reveals the Role of Fumarate in Regulating the Virulence of Enterohemorrhagic Escherichia Coli Cell Death & Disease. Mar, 2018 | Pubmed ID: 29515100 Neuroprotective Effects of Betulin in Pharmacological and Transgenic Caenorhabditis Elegans Models of Parkinson's Disease Cell Transplantation. Dec, 2017 | Pubmed ID: 29390878 Design and Synthesis of Malonamide Derivatives As Antibiotics Against Methicillin-Resistant Staphylococcus Aureus Molecules (Basel, Switzerland). Dec, 2017 | Pubmed ID: 29271946 HLH-30/TFEB-mediated Autophagy Functions in a Cell-autonomous Manner for Epithelium Intrinsic Cellular Defense Against Bacterial Pore-forming Toxin in C. Elegans Autophagy. Feb, 2017 | Pubmed ID: 27875098 A Disease Model of Muscle Necrosis Caused ByInfection In Frontiers in Microbiology. 2016 | Pubmed ID: 28101079 Mutation of the Enterohemorrhagic Escherichia Coli Core LPS Biosynthesis Enzyme RfaD Confers Hypersusceptibility to Host Intestinal Innate Immunity In Vivo Frontiers in Cellular and Infection Microbiology. 2016 | Pubmed ID: 27570746 Exercise in an Electrotactic Flow Chamber Ameliorates Age-related Degeneration in Caenorhabditis Elegans Scientific Reports. Jun, 2016 | Pubmed ID: 27305857 In Vitro and in Vivo Activity of a Novel Sorafenib Derivative SC5005 Against MRSA The Journal of Antimicrobial Chemotherapy. Feb, 2016 | Pubmed ID: 26553845 Loss of DNase II Function in the Gonad is Associated with a Higher Expression of Antimicrobial Genes in Caenorhabditis Elegans The Biochemical Journal. Aug, 2015 | Pubmed ID: 26251453 Aeromonas Stool Isolates from Individuals with or Without Diarrhea in Southern Taiwan: Predominance of Aeromonas Veronii Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. Dec, 2015 | Pubmed ID: 25440979 Virulence Diversity Among Bacteremic Aeromonas Isolates: Ex Vivo, Animal, and Clinical Evidences PloS One. 2014 | Pubmed ID: 25375798 N-butylidenephthalide Protects Against Dopaminergic Neuron Degeneration and α-synuclein Accumulation in Caenorhabditis Elegans Models of Parkinson's Disease PloS One. 2014 | Pubmed ID: 24416384 Acetylcorynoline Attenuates Dopaminergic Neuron Degeneration and α-synuclein Aggregation in Animal Models of Parkinson's Disease Neuropharmacology. Jul, 2014 | Pubmed ID: 23973292 Immobilization of the Nematode Caenorhabditis Elegans with Addressable Light-induced Heat Knockdown (ALINK) Lab on a Chip. Aug, 2013 | Pubmed ID: 23719845 Histone Deacetylase Inhibitor AR42 Regulates Telomerase Activity in Human Glioma Cells Via an Akt-dependent Mechanism Biochemical and Biophysical Research Communications. May, 2013 | Pubmed ID: 23624506 SESN-1 is a Positive Regulator of Lifespan in Caenorhabditis Elegans Experimental Gerontology. Mar, 2013 | Pubmed ID: 23318476 Genome Sequence of a Novel Human Pathogen, Aeromonas Aquariorum Journal of Bacteriology. Aug, 2012 | Pubmed ID: 22815437 WWP-1 is a Novel Modulator of the DAF-2 Insulin-like Signaling Network Involved in Pore-forming Toxin Cellular Defenses in Caenorhabditis Elegans PloS One. Mar, 2010 | Pubmed ID: 20209166 Evaluating Virulence and Pathogenesis of Aeromonas Infection in a Caenorhabditis elegans Model Yi-Wei Chen1, Wen-Chien Ko1,2, Chang-Shi Chen1,3, Po-Lin Chen2,4 1Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 3Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 4Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University JoVE 58768 Imunologia e Infecção Detection of Enterohemorrhagic Escherichia Coli Colonization in Murine Host by Non-invasive In Vivo Bioluminescence System Cheng-Ju Kuo1,2, Sin-Tian Wang1,2, Chang-Shi Chen1,2 1Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University JoVE 56169 Imunologia e Infecção
Evaluating Virulence and Pathogenesis of Aeromonas Infection in a Caenorhabditis elegans Model Yi-Wei Chen1, Wen-Chien Ko1,2, Chang-Shi Chen1,3, Po-Lin Chen2,4 1Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 3Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 4Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University JoVE 58768 Imunologia e Infecção
Detection of Enterohemorrhagic Escherichia Coli Colonization in Murine Host by Non-invasive In Vivo Bioluminescence System Cheng-Ju Kuo1,2, Sin-Tian Wang1,2, Chang-Shi Chen1,2 1Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University JoVE 56169 Imunologia e Infecção