Johnny Huard Stem Cell Research Center, Department of Orthopaedic Surgery University of Pittsburgh Biography Publications Institution JoVE Articles Johnny Huard has not added a biography. If you are Johnny Huard and would like to personalize this page please email our Author Liaison for assistance. Publications MTOR Signaling Plays a Critical Role in the Defects Observed in Muscle-derived Stem/progenitor Cells Isolated from a Murine Model of Accelerated Aging Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Aug, 2016 | Pubmed ID: 27572850 The Combined Use of Losartan and Muscle-Derived Stem Cells Significantly Improves the Functional Recovery of Muscle in a Young Mouse Model of Contusion Injuries The American Journal of Sports Medicine. Aug, 2016 | Pubmed ID: 27501834 Notch Signaling Mediates Skeletal Muscle Atrophy in Cancer Cachexia Caused by Osteosarcoma Sarcoma. 2016 | Pubmed ID: 27378829 Biological Therapies for Cartilage Lesions in the Hip: A New Horizon Orthopedics. Jul, 2016 | Pubmed ID: 27359284 Cyclooxygenase-2 Deficiency Impairs Muscle-derived Stem Cell-mediated Bone Regeneration Via Cellular Autonomous and Non-autonomous Mechanisms Human Molecular Genetics. Jun, 2016 | Pubmed ID: 27354351 Customized Platelet-rich Plasma with Transforming Growth Factor β1 Neutralization Antibody to Reduce Fibrosis in Skeletal Muscle Biomaterials. May, 2016 | Pubmed ID: 26923362 Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells Sarcoma. 2015 | Pubmed ID: 26819566 Controlled Dual Delivery of Fibroblast Growth Factor-2 and Interleukin-10 by Heparin-based Coacervate Synergistically Enhances Ischemic Heart Repair Biomaterials. Dec, 2015 | Pubmed ID: 26370927 Stem Cells Isolated from Human Dental Pulp and Amniotic Fluid Improve Skeletal Muscle Histopathology in Mdx/SCID Mice Stem Cell Research & Therapy. 2015 | Pubmed ID: 26316011 Regenerative Translation of Human Blood-Vessel-Derived MSC Precursors Stem Cells International. 2015 | Pubmed ID: 26273304 MMP1 Gene Expression Enhances Myoblast Migration and Engraftment Following Implanting into Mdx/SCID Mice Cell Adhesion & Migration. 2015 | Pubmed ID: 26223276 Two-stage Therapeutic Utility of Ectopically Formed Bone Tissue in Skeletal Muscle Induced by Adeno-associated Virus Containing Bone Morphogenetic Protein-4 Gene Journal of Orthopaedic Surgery and Research. 2015 | Pubmed ID: 26024920 The Effect of Blocking Angiogenesis on Anterior Cruciate Ligament Healing Following Stem Cell Transplantation Biomaterials. Aug, 2015 | Pubmed ID: 25965282 Gene and Cell Therapy for Muscle Regeneration Current Reviews in Musculoskeletal Medicine. Jun, 2015 | Pubmed ID: 25899573 Activation of Non-myogenic Mesenchymal Stem Cells During the Disease Progression in Dystrophic Dystrophin/utrophin Knockout Mice Human Molecular Genetics. Jul, 2015 | Pubmed ID: 25859011 Gene Therapy Approaches to Regenerating the Musculoskeletal System Nature Reviews. Rheumatology. Apr, 2015 | Pubmed ID: 25776949 The Role of Stem Cells and Tissue Engineering in Orthopaedic Sports Medicine: Current Evidence and Future Directions Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. May, 2015 | Pubmed ID: 25726331 The Role of Notch Signaling in Muscle Progenitor Cell Depletion and the Rapid Onset of Histopathology in Muscular Dystrophy Human Molecular Genetics. May, 2015 | Pubmed ID: 25678553 Biologic Strategies to Improve Nerve Regeneration After Peripheral Nerve Repair Journal of Reconstructive Microsurgery. May, 2015 | Pubmed ID: 25503421 Human Myocardial Pericytes: Multipotent Mesodermal Precursors Exhibiting Cardiac Specificity Stem Cells (Dayton, Ohio). Feb, 2015 | Pubmed ID: 25336400 Does Fibrin Clot Really Enhance Graft Healing After Double-bundle ACL Reconstruction in a Caprine Model? Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA. Mar, 2015 | Pubmed ID: 25326761 Characterization of a Compartment Syndrome-like Injury Model Muscle & Nerve. May, 2015 | Pubmed ID: 25242666 Local Intra-articular Injection of Rapamycin Delays Articular Cartilage Degeneration in a Murine Model of Osteoarthritis Arthritis Research & Therapy. 2014 | Pubmed ID: 25403236 ALDH Activity Correlates with Metastatic Potential in Primary Sarcomas of Bone Journal of Cancer Therapy. Mar, 2014 | Pubmed ID: 25328803 Stem Cell Therapy. Use of Differentiated Pluripotent Stem Cells As Replacement Therapy for Treating Disease Science (New York, N.Y.). Aug, 2014 | Pubmed ID: 25146295 Involvement of ERCC1 in the Pathogenesis of Osteoarthritis Through the Modulation of Apoptosis and Cellular Senescence Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2014 | Pubmed ID: 24964749 A Comparison of Bone Regeneration with Human Mesenchymal Stem Cells and Muscle-derived Stem Cells and the Critical Role of BMP Biomaterials. Aug, 2014 | Pubmed ID: 24856105 Role of Donor and Host Cells in Muscle-derived Stem Cell-mediated Bone Repair: Differentiation Vs. Paracrine Effects FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2014 | Pubmed ID: 24843069 Rapid Depletion of Muscle Progenitor Cells in Dystrophic Mdx/utrophin-/- Mice Human Molecular Genetics. Sep, 2014 | Pubmed ID: 24781208 Human Muscle-derived Stem/progenitor Cells Promote Functional Murine Peripheral Nerve Regeneration The Journal of Clinical Investigation. Apr, 2014 | Pubmed ID: 24642464 Development of a Web Course on Gene Therapy by the International Consortium of Gene Therapy Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2014 | Pubmed ID: 24584076 Chick Embryo Extract Demethylates Tumor Suppressor Genes in Osteosarcoma Cells Clinical Orthopaedics and Related Research. Mar, 2014 | Pubmed ID: 23761177 The Microenvironment-specific Transformation of Adult Stem Cells Models Malignant Triton Tumors PloS One. 2013 | Pubmed ID: 24349213 Stem Cells, Angiogenesis and Muscle Healing: a Potential Role in Massage Therapies? Postgraduate Medical Journal. Nov, 2013 | Pubmed ID: 24129034 Cellular Kinetics of Perivascular MSC Precursors Stem Cells International. 2013 | Pubmed ID: 24023546 The Role of Antioxidation and Immunomodulation in Postnatal Multipotent Stem Cell-mediated Cardiac Repair International Journal of Molecular Sciences. 2013 | Pubmed ID: 23924945 Sustained Release of Bone Morphogenetic Protein 2 Via Coacervate Improves the Osteogenic Potential of Muscle-derived Stem Cells Stem Cells Translational Medicine. Sep, 2013 | Pubmed ID: 23884640 Notch Signaling is Associated with ALDH Activity and an Aggressive Metastatic Phenotype in Murine Osteosarcoma Cells Frontiers in Oncology. 2013 | Pubmed ID: 23805413 Use of an Antifibrotic Agent Improves the Effect of Platelet-rich Plasma on Muscle Healing After Injury The Journal of Bone and Joint Surgery. American Volume. Jun, 2013 | Pubmed ID: 23780535 Platelet-rich Plasma Promotes the Proliferation of Human Muscle Derived Progenitor Cells and Maintains Their Stemness PloS One. 2013 | Pubmed ID: 23762264 Beneficial Effect of Mechanical Stimulation on the Regenerative Potential of Muscle-derived Stem Cells is Lost by Inhibiting Vascular Endothelial Growth Factor Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2013 | Pubmed ID: 23723372 RhoA Mediates Defective Stem Cell Function and Heterotopic Ossification in Dystrophic Muscle of Mice FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2013 | Pubmed ID: 23704088 Tendon Graft Revitalization Using Adult Anterior Cruciate Ligament (ACL)-derived CD34+ Cell Sheets for ACL Reconstruction Biomaterials. Jul, 2013 | Pubmed ID: 23632324 Human Myogenic Endothelial Cells Exhibit Chondrogenic and Osteogenic Potentials at the Clonal Level Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2013 | Pubmed ID: 23553740 Muscle-derived Stem/progenitor Cell Dysfunction in Zmpste24-deficient Progeroid Mice Limits Muscle Regeneration Stem Cell Research & Therapy. 2013 | Pubmed ID: 23531345 Neuromuscular Electrical Stimulation As a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle PloS One. 2013 | Pubmed ID: 23526927 Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells Sarcoma. 2013 | Pubmed ID: 23476113 Isolation of Muscle-derived Stem/progenitor Cells Based on Adhesion Characteristics to Collagen-coated Surfaces Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23400434 Translating the Genomics Revolution: the Need for an International Gene Therapy Consortium for Monogenic Diseases Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2013 | Pubmed ID: 23369965 Muscle-derived Stem Cell Sheets Support Pump Function and Prevent Cardiac Arrhythmias in a Model of Chronic Myocardial Infarction Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2013 | Pubmed ID: 23319053 Therapeutic Advantage in Selective Ligament Augmentation for Partial Tears of the Anterior Cruciate Ligament: Results in an Animal Model The American Journal of Sports Medicine. Feb, 2013 | Pubmed ID: 23299851 The Use of Blood Vessel-derived Stem Cells for Meniscal Regeneration and Repair Medicine and Science in Sports and Exercise. May, 2013 | Pubmed ID: 23247715 The Effect of a Heparin-based Coacervate of Fibroblast Growth Factor-2 on Scarring in the Infarcted Myocardium Biomaterials. Feb, 2013 | Pubmed ID: 23211448 Stem Cells, Angiogenesis and Muscle Healing: a Potential Role in Massage Therapies? British Journal of Sports Medicine. Jun, 2013 | Pubmed ID: 23197410 Human Pericytes for Ischemic Heart Repair Stem Cells (Dayton, Ohio). Feb, 2013 | Pubmed ID: 23165704 The Timing of Administration of a Clinically Relevant Dose of Losartan Influences the Healing Process After Contusion Induced Muscle Injury Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2013 | Pubmed ID: 23154994 Dystrophin and Utrophin "double Knockout" Dystrophic Mice Exhibit a Spectrum of Degenerative Musculoskeletal Abnormalities Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2013 | Pubmed ID: 23097179 BMP2 is Superior to BMP4 for Promoting Human Muscle Derived-stem Cell Mediated Bone Regeneration in a Critical Size Calvarial Defect Model Cell Transplantation. Nov, 2012 | Pubmed ID: 23244588 Developing Cardiac and Skeletal Muscle Share Fast-skeletal Myosin Heavy Chain and Cardiac Troponin-I Expression PloS One. 2012 | Pubmed ID: 22808244 Therapeutic Potential of Anterior Cruciate Ligament-derived Stem Cells for Anterior Cruciate Ligament Reconstruction Cell Transplantation. 2012 | Pubmed ID: 22732227 Effect of Host Sex and Sex Hormones on Muscle-derived Stem Cell-mediated Bone Formation and Defect Healing Tissue Engineering. Part A. Sep, 2012 | Pubmed ID: 22712541 NF-κB Inhibition Delays DNA Damage-induced Senescence and Aging in Mice The Journal of Clinical Investigation. Jul, 2012 | Pubmed ID: 22706308 Timing of the Administration of Suramin Treatment After Muscle Injury Muscle & Nerve. Jul, 2012 | Pubmed ID: 22644812 Human Blood-vessel-derived Stem Cells for Tissue Repair and Regeneration Journal of Biomedicine & Biotechnology. 2012 | Pubmed ID: 22500099 Isolation of Myogenic Stem Cells from Cultures of Cryopreserved Human Skeletal Muscle Cell Transplantation. 2012 | Pubmed ID: 22472558 Biological Approaches to Improve Skeletal Muscle Healing After Injury and Disease Birth Defects Research. Part C, Embryo Today : Reviews. Mar, 2012 | Pubmed ID: 22457179 Mechanical Loading of Stem Cells for Improvement of Transplantation Outcome: The Role of Loading History Tissue Engineering. Part A. Jan, 2012 | Pubmed ID: 22280442 Biologic Approaches to Enhance Rotator Cuff Healing After Injury Journal of Shoulder and Elbow Surgery / American Shoulder and Elbow Surgeons ... [et Al.]. Feb, 2012 | Pubmed ID: 22244061 Muscle-derived Stem/progenitor Cell Dysfunction Limits Healthspan and Lifespan in a Murine Progeria Model Nature Communications. 2012 | Pubmed ID: 22215083 Human Skeletal Muscle Cells with a Slow Adhesion Rate After Isolation and an Enhanced Stress Resistance Improve Function of Ischemic Hearts Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2012 | Pubmed ID: 22068427 Role of Angiogenesis After Muscle Derived Stem Cell Transplantation in Injured Medial Collateral Ligament Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Apr, 2012 | Pubmed ID: 21913220 Murine and Human Myogenic Cells Identified by Elevated Aldehyde Dehydrogenase Activity: Implications for Muscle Regeneration and Repair PloS One. 2011 | Pubmed ID: 22195027 NF-κB Negatively Impacts the Myogenic Potential of Muscle-derived Stem Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2011 | Pubmed ID: 22158056 Skeletal Muscle-derived Stem Cells: Implications for Cell-mediated Therapies Medicina (Kaunas, Lithuania). 2011 | Pubmed ID: 22156603 Venous Graft-derived Cells Participate in Peripheral Nerve Regeneration PloS One. 2011 | Pubmed ID: 21966370 Intramuscular Transplantation of Muscle-derived Stem Cells Accelerates Skeletal Muscle Healing After Contusion Injury Via Enhancement of Angiogenesis The American Journal of Sports Medicine. Sep, 2011 | Pubmed ID: 21828363 Injectable Fibroblast Growth Factor-2 Coacervate for Persistent Angiogenesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21808045 Terminal Differentiation is Not a Major Determinant for the Success of Stem Cell Therapy - Cross-talk Between Muscle-derived Stem Cells and Host Cells Stem Cell Research & Therapy. 2011 | Pubmed ID: 21745421 Isolation and Characterization of Human Anterior Cruciate Ligament-Derived Vascular Stem Cells Stem Cells and Development. Aug, 2011 | Pubmed ID: 21732814 Identification and Characterization of Chondrogenic Progenitor Cells in the Fascia of Postnatal Skeletal Muscle Journal of Molecular Cell Biology. Dec, 2011 | Pubmed ID: 21729867 Follistatin Improves Skeletal Muscle Healing After Injury and Disease Through an Interaction with Muscle Regeneration, Angiogenesis, and Fibrosis The American Journal of Pathology. Aug, 2011 | Pubmed ID: 21689628 Use of an Ultrasonic Blade Facilitates Muscle Repair After Incision Injury The Journal of Surgical Research. May, 2011 | Pubmed ID: 21324491 Engineering Spatial Control of Multiple Differentiation Fates Within a Stem Cell Population Biomaterials. May, 2011 | Pubmed ID: 21316755 Study of Muscle Cell Dedifferentiation After Skeletal Muscle Injury of Mice with a Cre-Lox System PloS One. 2011 | Pubmed ID: 21304901 Lentivirus-mediated Wnt11 Gene Transfer Enhances Cardiomyogenic Differentiation of Skeletal Muscle-derived Stem Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2011 | Pubmed ID: 21304494 Placental Perivascular Cells for Human Muscle Regeneration Stem Cells and Development. Mar, 2011 | Pubmed ID: 20923371 IOC Consensus Paper on the Use of Platelet-rich Plasma in Sports Medicine British Journal of Sports Medicine. Dec, 2010 | Pubmed ID: 21106774 Accelerated Aging of Intervertebral Discs in a Mouse Model of Progeria Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2010 | Pubmed ID: 20973062 Skeletal Muscle-derived Stem Cells Differentiate into Hepatocyte-like Cells and Aid in Liver Regeneration International Journal of Clinical and Experimental Pathology. 2010 | Pubmed ID: 20830239 Pericyte-based Human Tissue Engineered Vascular Grafts Biomaterials. Nov, 2010 | Pubmed ID: 20684982 Differential Efficacy of Gels Derived from Small Intestinal Submucosa As an Injectable Biomaterial for Myocardial Infarct Repair Biomaterials. Oct, 2010 | Pubmed ID: 20674011 Cellular Antioxidant Levels Influence Muscle Stem Cell Therapy Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2010 | Pubmed ID: 20664528 Effect of Phosphatidyl Inositol 3-kinase, Extracellular Signal-regulated Kinases 1/2, and P38 Mitogen-activated Protein Kinase Inhibition on Osteogenic Differentiation of Muscle-derived Stem Cells Tissue Engineering. Part A. Dec, 2010 | Pubmed ID: 20617875 Testing the Critical Size in Calvarial Bone Defects: Revisiting the Concept of a Critical-size Defect Plastic and Reconstructive Surgery. Jun, 2010 | Pubmed ID: 20517092 Platelets in Regeneration Seminars in Thrombosis and Hemostasis. Mar, 2010 | Pubmed ID: 20414833 AAV-directed Muscular Dystrophy Gene Therapy Expert Opinion on Biological Therapy. Mar, 2010 | Pubmed ID: 20132060 Inkjet-based Biopatterning of Bone Morphogenetic Protein-2 to Spatially Control Calvarial Bone Formation Tissue Engineering. Part A. May, 2010 | Pubmed ID: 20028232 In Vivo Assessment of a Tissue-engineered Vascular Graft Combining a Biodegradable Elastomeric Scaffold and Muscle-derived Stem Cells in a Rat Model Tissue Engineering. Part A. Apr, 2010 | Pubmed ID: 19895206 The Synergistic Effect of Treadmill Running on Stem-cell Transplantation to Heal Injured Skeletal Muscle Tissue Engineering. Part A. Mar, 2010 | Pubmed ID: 19788347 A Three-dimensional Gel Bioreactor for Assessment of Cardiomyocyte Induction in Skeletal Muscle-derived Stem Cells Tissue Engineering. Part C, Methods. Jun, 2010 | Pubmed ID: 19601695 Perivascular Multi-lineage Progenitor Cells in Human Organs: Regenerative Units, Cytokine Sources or Both? Cytokine & Growth Factor Reviews. Oct-Dec, 2009 | Pubmed ID: 19926515 Effect of VEGF on the Regenerative Capacity of Muscle Stem Cells in Dystrophic Skeletal Muscle Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2009 | Pubmed ID: 19603004 Sex of Muscle Stem Cells Does Not Influence Potency for Cardiac Cell Therapy Cell Transplantation. 2009 | Pubmed ID: 19523348 Cartilage Repair in a Rat Model of Osteoarthritis Through Intraarticular Transplantation of Muscle-derived Stem Cells Expressing Bone Morphogenetic Protein 4 and Soluble Flt-1 Arthritis and Rheumatism. May, 2009 | Pubmed ID: 19404941 The Dose of Growth Factors Influences the Synergistic Effect of Vascular Endothelial Growth Factor on Bone Morphogenetic Protein 4-induced Ectopic Bone Formation Tissue Engineering. Part A. Aug, 2009 | Pubmed ID: 19215221 Ex Vivo Noggin Gene Therapy Inhibits Bone Formation in a Mouse Model of Postoperative Resynostosis Plastic and Reconstructive Surgery. Feb, 2009 | Pubmed ID: 19182668 The Effect of Muscle Loading on Skeletal Muscle Regenerative Potential: an Update of Current Research Findings Relating to Aging and Neuromuscular Pathology American Journal of Physical Medicine & Rehabilitation / Association of Academic Physiatrists. Feb, 2009 | Pubmed ID: 19169178 Functional Overloading of Dystrophic Mice Enhances Muscle-derived Stem Cell Contribution to Muscle Contractile Capacity Archives of Physical Medicine and Rehabilitation. Jan, 2009 | Pubmed ID: 19154831 Blocking Vascular Endothelial Growth Factor with Soluble Flt-1 Improves the Chondrogenic Potential of Mouse Skeletal Muscle-derived Stem Cells Arthritis and Rheumatism. Jan, 2009 | Pubmed ID: 19116905 Stem Cells for the Treatment of Skeletal Muscle Injury Clinics in Sports Medicine. Jan, 2009 | Pubmed ID: 19064161 Bone Regeneration Mediated by BMP4-expressing Muscle-derived Stem Cells is Affected by Delivery System Tissue Engineering. Part A. Feb, 2009 | Pubmed ID: 19061430 Antioxidant Levels Represent a Major Determinant in the Regenerative Capacity of Muscle Stem Cells Molecular Biology of the Cell. Jan, 2009 | Pubmed ID: 19005220 Re: Angiotensin II Receptor Blockade Administered After Injury Improves Muscle Regeneration and Decreases Fibrosis in Normal Skeletal Muscle The American Journal of Sports Medicine. Dec, 2008 | Pubmed ID: 19074403 Myogenic Endothelial Cells Purified from Human Skeletal Muscle Improve Cardiac Function After Transplantation into Infarcted Myocardium Journal of the American College of Cardiology. Dec, 2008 | Pubmed ID: 19038685 The Influence of Sex on the Chondrogenic Potential of Muscle-derived Stem Cells: Implications for Cartilage Regeneration and Repair Arthritis and Rheumatism. Dec, 2008 | Pubmed ID: 19035511 A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs Cell Stem Cell. Sep, 2008 | Pubmed ID: 18786417 Isolation of a Slowly Adhering Cell Fraction Containing Stem Cells from Murine Skeletal Muscle by the Preplate Technique Nature Protocols. 2008 | Pubmed ID: 18772878 Purification and Culture of Human Blood Vessel-associated Progenitor Cells Current Protocols in Stem Cell Biology. Mar, 2008 | Pubmed ID: 18770640 Improved Muscle Healing After Contusion Injury by the Inhibitory Effect of Suramin on Myostatin, a Negative Regulator of Muscle Growth The American Journal of Sports Medicine. Dec, 2008 | Pubmed ID: 18725651 Angiotensin II Receptor Blockade Administered After Injury Improves Muscle Regeneration and Decreases Fibrosis in Normal Skeletal Muscle The American Journal of Sports Medicine. Aug, 2008 | Pubmed ID: 18550776 Purification and Long-term Culture of Multipotent Progenitor Cells Affiliated with the Walls of Human Blood Vessels: Myoendothelial Cells and Pericytes Methods in Cell Biology. 2008 | Pubmed ID: 18442653 Matrix Metalloproteinase-1 Treatment of Muscle Fibrosis Acta Biomaterialia. Sep, 2008 | Pubmed ID: 18440885 Dominant Negative Bmp5 Mutation Reveals Key Role of BMPs in Skeletal Response to Mechanical Stimulation BMC Developmental Biology. 2008 | Pubmed ID: 18380899 Sex Differences in Muscle-derived Stem Cells and Skeletal Muscle Critical Reviews in Eukaryotic Gene Expression. 2008 | Pubmed ID: 18304031 Regenerative Medicine for the Musculoskeletal System Based on Muscle-derived Stem Cells The Journal of the American Academy of Orthopaedic Surgeons. Feb, 2008 | Pubmed ID: 18252837 Development of a Tissue-engineered Vascular Graft Combining a Biodegradable Scaffold, Muscle-derived Stem Cells and a Rotational Vacuum Seeding Technique Biomaterials. Mar, 2008 | Pubmed ID: 18035412 In Vitro Interaction Between Muscle-derived Stem Cells and Nucleus Pulposus Cells The Spine Journal : Official Journal of the North American Spine Society. Sep-Oct, 2008 | Pubmed ID: 18023623 Microenvironments Engineered by Inkjet Bioprinting Spatially Direct Adult Stem Cells Toward Muscle- and Bone-like Subpopulations Stem Cells (Dayton, Ohio). Jan, 2008 | Pubmed ID: 17901398 Interaction Between Macrophages, TGF-beta1, and the COX-2 Pathway During the Inflammatory Phase of Skeletal Muscle Healing After Injury Journal of Cellular Physiology. Feb, 2008 | Pubmed ID: 17657727 A Relationship Between Vascular Endothelial Growth Factor, Angiogenesis, and Cardiac Repair After Muscle Stem Cell Transplantation into Ischemic Hearts Journal of the American College of Cardiology. Oct, 2007 | Pubmed ID: 17950150 [The Sex of Muscle Stem Cells: Must It Be Taken into Account?] Médecine Sciences : M/S. Oct, 2007 | Pubmed ID: 17937884 Muscle-derived Stem Cells for Tissue Engineering and Regenerative Therapy Biomaterials. Dec, 2007 | Pubmed ID: 17915311 Prospective Identification of Myogenic Endothelial Cells in Human Skeletal Muscle Nature Biotechnology. Sep, 2007 | Pubmed ID: 17767154 Decorin Gene Transfer Promotes Muscle Cell Differentiation and Muscle Regeneration Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2007 | Pubmed ID: 17609657 Osteogenic Potential of Postnatal Skeletal Muscle-derived Stem Cells is Influenced by Donor Sex Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2007 | Pubmed ID: 17605633 Relationships Between Transforming Growth Factor-beta1, Myostatin, and Decorin: Implications for Skeletal Muscle Fibrosis The Journal of Biological Chemistry. Aug, 2007 | Pubmed ID: 17597062 Skeletal Muscle Fiber Type Conversion During the Repair of Mouse Soleus: Potential Implications for Muscle Healing After Injury Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Nov, 2007 | Pubmed ID: 17593537 Malignant Transformation of Multipotent Muscle-derived Cells by Concurrent Differentiation Signals Stem Cells (Dayton, Ohio). Sep, 2007 | Pubmed ID: 17569791 Regenerative Medicine in Orthopaedic Surgery Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2007 | Pubmed ID: 17551972 Matrix Metalloproteinase-1 Therapy Improves Muscle Healing Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2007 | Pubmed ID: 17551103 Noggin Inhibits Postoperative Resynostosis in Craniosynostotic Rabbits Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2007 | Pubmed ID: 17437358 A Role for Cell Sex in Stem Cell-mediated Skeletal Muscle Regeneration: Female Cells Have Higher Muscle Regeneration Efficiency The Journal of Cell Biology. Apr, 2007 | Pubmed ID: 17420291 Thermosensitive Hydrogel PEG-PLGA-PEG Enhances Engraftment of Muscle-derived Stem Cells and Promotes Healing in Diabetic Wound Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2007 | Pubmed ID: 17406344 Stem and Progenitor Cells in Skeletal Muscle Development, Maintenance, and Therapy Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2007 | Pubmed ID: 17387336 Tissue Engineering and Developmental Biology: Going Biomimetic Tissue Engineering. Dec, 2006 | Pubmed ID: 17518669 Mixed Metastatic Lung Cancer Lesions in Bone Are Inhibited by Noggin Overexpression and Rank:Fc Administration Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2006 | Pubmed ID: 16995812 Gene Therapy and Tissue Engineering in Orthopaedic Surgery Instructional Course Lectures. 2006 | Pubmed ID: 16958493 VEGF and BMP Expression in Mouse Osteosarcoma Cells Clinical Orthopaedics and Related Research. Sep, 2006 | Pubmed ID: 16906080 Periurethral Cellular Injection: Comparison of Muscle-derived Progenitor Cells and Fibroblasts with Regard to Efficacy and Tissue Contractility in an Animal Model of Stress Urinary Incontinence Urology. Aug, 2006 | Pubmed ID: 16904482 Mouse Adipose-derived Stem Cells Undergo Multilineage Differentiation in Vitro but Primarily Osteogenic and Chondrogenic Differentiation in Vivo Tissue Engineering. Jul, 2006 | Pubmed ID: 16889519 Inhibited Skeletal Muscle Healing in Cyclooxygenase-2 Gene-deficient Mice: the Role of PGE2 and PGF2alpha Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2006 | Pubmed ID: 16778000 Nerve Growth Factor Improves the Muscle Regeneration Capacity of Muscle Stem Cells in Dystrophic Muscle Human Gene Therapy. Feb, 2006 | Pubmed ID: 16454652 Cartilage Repair Using Bone Morphogenetic Protein 4 and Muscle-derived Stem Cells Arthritis and Rheumatism. Feb, 2006 | Pubmed ID: 16447218 Biomechanical Characterization of the Urethral Musculature American Journal of Physiology. Renal Physiology. May, 2006 | Pubmed ID: 16368741 Overexpression of Noggin Inhibits BMP-mediated Growth of Osteolytic Prostate Cancer Lesions Bone. Feb, 2006 | Pubmed ID: 16126463 Cutting-edge Muscle Recovery: Using Antifibrosis Agents to Improve Healing The Physician and Sportsmedicine. May, 2005 | Pubmed ID: 20086363 Musculoskeletal Gene Therapy and Its Potential Use in the Treatment of Complicated Musculoskeletal Infection Infectious Disease Clinics of North America. Dec, 2005 | Pubmed ID: 16297745 Influence of BMPs on the Formation of Osteoblastic Lesions in Metastatic Prostate Cancer Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2005 | Pubmed ID: 16294272 VEGF Improves, Whereas SFlt1 Inhibits, BMP2-induced Bone Formation and Bone Healing Through Modulation of Angiogenesis Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Nov, 2005 | Pubmed ID: 16234975 Cell Therapy for Muscle Regeneration and Repair Physical Medicine and Rehabilitation Clinics of North America. Nov, 2005 | Pubmed ID: 16214050 NS-398, a Cyclooxygenase-2-specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis The American Journal of Pathology. Oct, 2005 | Pubmed ID: 16192645 The Effect of Relaxin Treatment on Skeletal Muscle Injuries The American Journal of Sports Medicine. Dec, 2005 | Pubmed ID: 16157846 Differential Myocardial Infarct Repair with Muscle Stem Cells Compared to Myoblasts Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2005 | Pubmed ID: 16125468 Initial Failure in Myoblast Transplantation Therapy Has Led the Way Toward the Isolation of Muscle Stem Cells: Potential for Tissue Regeneration Current Topics in Developmental Biology. 2005 | Pubmed ID: 16125002 Differential Effect of BMP4 on NIH/3T3 and C2C12 Cells: Implications for Endochondral Bone Formation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Sep, 2005 | Pubmed ID: 16059633 Noggin Improves Bone Healing Elicited by Muscle Stem Cells Expressing Inducible BMP4 Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2005 | Pubmed ID: 16043095 The Vascular Wall As a Source of Stem Cells Annals of the New York Academy of Sciences. Jun, 2005 | Pubmed ID: 15958696 The Use of Suramin, an Antifibrotic Agent, to Improve Muscle Recovery After Strain Injury The American Journal of Sports Medicine. Jan, 2005 | Pubmed ID: 15610998 Biaxial Mechanical Properties of Muscle-derived Cell Seeded Small Intestinal Submucosa for Bladder Wall Reconstitution Biomaterials. Feb, 2005 | Pubmed ID: 15275818 Noninvasive Monitoring and Tracking of Muscle Stem Cell Transplants Transplantation. Dec, 2004 | Pubmed ID: 15591951 Tissue Engineering with Muscle-derived Stem Cells Current Opinion in Biotechnology. Oct, 2004 | Pubmed ID: 15464371 Structural and Functional Healing of Critical-size Segmental Bone Defects by Transduced Muscle-derived Cells Expressing BMP4 The Journal of Gene Medicine. Sep, 2004 | Pubmed ID: 15352071 Development of a Self-inactivating Tet-on Retroviral Vector Expressing Bone Morphogenetic Protein 4 to Achieve Regulated Bone Formation Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2004 | Pubmed ID: 15194055 Ex Vivo Gene Therapy-induced Endochondral Bone Formation: Comparison of Muscle-derived Stem Cells and Different Subpopulations of Primary Muscle-derived Cells Bone. Jun, 2004 | Pubmed ID: 15193544 Muscle-derived Stem Cells for Musculoskeletal Tissue Regeneration and Repair Transplant Immunology. Apr, 2004 | Pubmed ID: 15157924 Intraurethral Muscle-derived Cell Injections Increase Leak Point Pressure in a Rat Model of Intrinsic Sphincter Deficiency Urology. Apr, 2004 | Pubmed ID: 15072911 Converse Relationship Between in Vitro Osteogenic Differentiation and in Vivo Bone Healing Elicited by Different Populations of Muscle-derived Cells Genetically Engineered to Express BMP4 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Apr, 2004 | Pubmed ID: 15005851 Transforming Growth Factor-beta1 Induces the Differentiation of Myogenic Cells into Fibrotic Cells in Injured Skeletal Muscle: a Key Event in Muscle Fibrogenesis The American Journal of Pathology. Mar, 2004 | Pubmed ID: 14982854 Ex Vivo Gene Transfer to Mature Skeletal Muscle by Using Adenovirus Helper Cells The Journal of Gene Medicine. Feb, 2004 | Pubmed ID: 14978769 Gene Transfer to Skeletal Muscle Using Herpes Simplex Virus-based Vectors Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 14970600 Establishing Reliable Criteria for Isolating Myogenic Cell Fractions with Stem Cell Properties and Enhanced Regenerative Capacity Blood Cells, Molecules & Diseases. Jan-Feb, 2004 | Pubmed ID: 14757409 Noninvasive Monitoring of Stem Cell Transfer for Muscle Disorders Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Feb, 2004 | Pubmed ID: 14755651 Muscle-derived Stem Cells Cell Cycle (Georgetown, Tex.). Feb, 2004 | Pubmed ID: 14712064 Retroviral Delivery of Noggin Inhibits the Formation of Heterotopic Ossification Induced by BMP-4, Demineralized Bone Matrix, and Trauma in an Animal Model The Journal of Bone and Joint Surgery. American Volume. Jan, 2004 | Pubmed ID: 14711949 Development of an Experimental System for the Study of Urethral Biomechanical Function American Journal of Physiology. Renal Physiology. Feb, 2004 | Pubmed ID: 14506075 Muscle-derived Stem Cells: Potential for Muscle Regeneration Birth Defects Research. Part C, Embryo Today : Reviews. Aug, 2003 | Pubmed ID: 14671776 Improved Sphincter Contractility After Allogenic Muscle-derived Progenitor Cell Injection into the Denervated Rat Urethra Urology. Nov, 2003 | Pubmed ID: 14624934 Dystrophin Delivery in Dystrophin-deficient DMDmdx Skeletal Muscle by Isogenic Muscle-derived Stem Cell Transplantation Human Gene Therapy. Nov, 2003 | Pubmed ID: 14577915 The Role of Cell Type in Bone Healing Mediated by Ex Vivo Gene Therapy Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Oct, 2003 | Pubmed ID: 14534793 Gene Therapy to Improve Osteogenesis in Bone Lesions with Severe Soft Tissue Damage Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Oct, 2003 | Pubmed ID: 14504931 Improvement of Muscle Healing Through Enhancement of Muscle Regeneration and Prevention of Fibrosis Muscle & Nerve. Sep, 2003 | Pubmed ID: 12929198 Gamma Interferon As an Antifibrosis Agent in Skeletal Muscle Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Sep, 2003 | Pubmed ID: 12919866 Stem Cells in the Treatment of Muscle and Connective Tissue Diseases Current Opinion in Pharmacology. Jun, 2003 | Pubmed ID: 12810201 Muscle-derived Stem Cells Seeded into Acellular Scaffolds Develop Calcium-dependent Contractile Activity That is Modulated by Nicotinic Receptors Urology. Jun, 2003 | Pubmed ID: 12809930 Muscle Stem Cells Differentiate into Haematopoietic Lineages but Retain Myogenic Potential Nature Cell Biology. Jul, 2003 | Pubmed ID: 12792651 Antifibrotic Effects of Suramin in Injured Skeletal Muscle After Laceration Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2003 | Pubmed ID: 12730151 Gene Therapy in Orthopaedic Surgery Instructional Course Lectures. 2003 | Pubmed ID: 12690900 Gene Therapy and Tissue Engineering for Sports Medicine The Journal of Gene Medicine. Feb, 2003 | Pubmed ID: 12539148 Muscle-based Gene Therapy and Tissue Engineering to Improve Bone Healing Clinical Orthopaedics and Related Research. Oct, 2002 | Pubmed ID: 12394474 Muscle Derived Cell Mediated Ex Vivo Gene Transfer to the Lower Urinary Tract: Comparison of Viral Vectors Urological Research. Oct, 2002 | Pubmed ID: 12389119 The Role of CD34 Expression and Cellular Fusion in the Regeneration Capacity of Myogenic Progenitor Cells Journal of Cell Science. Nov, 2002 | Pubmed ID: 12376567 Effect of Cryoinjury on the Contractile Parameters of Bladder Strips: a Model of Impaired Detrusor Contractility Brain Research Bulletin. Oct, 2002 | Pubmed ID: 12372544 Synergistic Enhancement of Bone Formation and Healing by Stem Cell-expressed VEGF and Bone Morphogenetic Protein-4 The Journal of Clinical Investigation. Sep, 2002 | Pubmed ID: 12235106 Muscle Derived, Cell Based Ex Vivo Gene Therapy for Treatment of Full Thickness Articular Cartilage Defects The Journal of Rheumatology. Sep, 2002 | Pubmed ID: 12233887 Gene Therapy and Tissue Engineering Based on Muscle-derived Stem Cells Current Opinion in Molecular Therapeutics. Aug, 2002 | Pubmed ID: 12222876 The American Journal of Pathology. Sep, 2002 | Pubmed ID: 12213718 Muscle-based Gene Therapy and Tissue Engineering for Treatment of Growth Plate Injuries Journal of Pediatric Orthopedics. Sep-Oct, 2002 | Pubmed ID: 12198455 BMP4-expressing Muscle-derived Stem Cells Differentiate into Osteogenic Lineage and Improve Bone Healing in Immunocompetent Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2002 | Pubmed ID: 12161183 Enhancement of Bone Healing Based on Ex Vivo Gene Therapy Using Human Muscle-derived Cells Expressing Bone Morphogenetic Protein 2 Human Gene Therapy. Jul, 2002 | Pubmed ID: 12133273 Adenovirus Mediated Gene Transfer to Skeletal Muscle Microscopy Research and Technique. Jul, 2002 | Pubmed ID: 12112422 Insulin Growth Factor-1 Decreases Muscle Atrophy Following Denervation Microsurgery. 2002 | Pubmed ID: 12111979 Enhancement of Tendon-bone Integration of Anterior Cruciate Ligament Grafts with Bone Morphogenetic Protein-2 Gene Transfer: a Histological and Biomechanical Study The Journal of Bone and Joint Surgery. American Volume. Jul, 2002 | Pubmed ID: 12107310 Identification of a Novel Population of Muscle Stem Cells in Mice: Potential for Muscle Regeneration The Journal of Cell Biology. May, 2002 | Pubmed ID: 12021255 The Use of Ex Vivo Gene Transfer Based on Muscle-derived Stem Cells for Cardiovascular Medicine Trends in Cardiovascular Medicine. Apr, 2002 | Pubmed ID: 12007736 Muscle Injuries and Repair: Current Trends in Research The Journal of Bone and Joint Surgery. American Volume. May, 2002 | Pubmed ID: 12004029 Genetic Engineering of Meniscal Allografts Tissue Engineering. Feb, 2002 | Pubmed ID: 11886659 Gene Therapy and Tissue Engineering in Orthopaedic Surgery The Journal of the American Academy of Orthopaedic Surgeons. Jan-Feb, 2002 | Pubmed ID: 11809046 Isolering af Perivaskulær multipotente precursorcelle populationer fra humant hjertevæv James E. Baily1, William C.W. Chen2,3, Nusrat Khan4, Iain R. Murray4, Zaniah N. González Galofre4, Johnny Huard5,6, Bruno Péault4,7 1Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, 2Department of Bioengineering and Orthopaedic Surgery, University of Pittsburgh, 3Research Laboratory of Electronics and Department of Biological Engineering, Massachusetts Institute of Technology, 4MRC Centre for Regenerative Medicine, University of Edinburgh, 5Stem Cell Research Center, Department of Orthopaedic Surgery, University of Pittsburgh, 6Department of Orthopaedic Surgery, University of Texas Health Science Center at Houston, 7Department of Orthopaedic Surgery, UCLA Orthopaedic Hospital, David Geffen School of Medicine, University of California at Los Angeles JoVE 54252 Biologia do Desenvolvimento Isolering af blod-fartøj-afledt Multipotente Forstadier fra human skeletmuskel William C.W. Chen1, Arman Saparov2,3, Mirko Corselli4, Mihaela Crisan5, Bo Zheng6, Bruno Péault7,8, Johnny Huard9 1Stem Cell Research Center, Department of Bioengineering and Orthopedic Surgery, University of Pittsburgh, 2Department of Orthopedic Surgery, University of Pittsburgh, 3Nazarbayev University Research and Innovation System, Nazarbayev University, 4Department of Orthopaedic Surgery, UCLA Orthopaedic Hospital and the Orthopaedic Hospital Research Center, University of California at Los Angeles, 5Department of Cell Biology, Erasmus MC Stem Cell Institute, 6OHSU Center for Regenerative Medicine, Oregon Health & Science University, 7Centre for Cardiovascular Science and MRC Centre for Regenerative Medicine, Queen's Medical Research Institute and University of Edinburgh, 8David Geffen School of Medicine and the Orthopaedic Hospital Research Center, University of California at Los Angeles, 9Stem Cell Research Center, Department of Orthopedic Surgery and McGowan Institute for Regenerative Medicine, University of Pittsburgh JoVE 51195 Biologia Isolating Stem Cells from Soft Musculoskeletal Tissues JoVE 2011 Biologia
Isolering af Perivaskulær multipotente precursorcelle populationer fra humant hjertevæv James E. Baily1, William C.W. Chen2,3, Nusrat Khan4, Iain R. Murray4, Zaniah N. González Galofre4, Johnny Huard5,6, Bruno Péault4,7 1Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, 2Department of Bioengineering and Orthopaedic Surgery, University of Pittsburgh, 3Research Laboratory of Electronics and Department of Biological Engineering, Massachusetts Institute of Technology, 4MRC Centre for Regenerative Medicine, University of Edinburgh, 5Stem Cell Research Center, Department of Orthopaedic Surgery, University of Pittsburgh, 6Department of Orthopaedic Surgery, University of Texas Health Science Center at Houston, 7Department of Orthopaedic Surgery, UCLA Orthopaedic Hospital, David Geffen School of Medicine, University of California at Los Angeles JoVE 54252 Biologia do Desenvolvimento
Isolering af blod-fartøj-afledt Multipotente Forstadier fra human skeletmuskel William C.W. Chen1, Arman Saparov2,3, Mirko Corselli4, Mihaela Crisan5, Bo Zheng6, Bruno Péault7,8, Johnny Huard9 1Stem Cell Research Center, Department of Bioengineering and Orthopedic Surgery, University of Pittsburgh, 2Department of Orthopedic Surgery, University of Pittsburgh, 3Nazarbayev University Research and Innovation System, Nazarbayev University, 4Department of Orthopaedic Surgery, UCLA Orthopaedic Hospital and the Orthopaedic Hospital Research Center, University of California at Los Angeles, 5Department of Cell Biology, Erasmus MC Stem Cell Institute, 6OHSU Center for Regenerative Medicine, Oregon Health & Science University, 7Centre for Cardiovascular Science and MRC Centre for Regenerative Medicine, Queen's Medical Research Institute and University of Edinburgh, 8David Geffen School of Medicine and the Orthopaedic Hospital Research Center, University of California at Los Angeles, 9Stem Cell Research Center, Department of Orthopedic Surgery and McGowan Institute for Regenerative Medicine, University of Pittsburgh JoVE 51195 Biologia