Ludvic Zrinzo Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery UCL Institute of Neurology Biography Publications Institution JoVE Articles Ludvic Zrinzo has not added a biography. If you are Ludvic Zrinzo and would like to personalize this page please email our Author Liaison for assistance. Publications Midline Frontal Cortex Low-frequency Activity Drives Subthalamic Nucleus Oscillations During Conflict The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2014 | Pubmed ID: 24849364 Long-term Outcome of Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease Using an MRI-guided and MRI-verified Approach Journal of Neurology, Neurosurgery, and Psychiatry. Apr, 2014 | Pubmed ID: 24790212 Letter to the Editor: Deep Brain Stimulation for Dystonia Journal of Neurosurgery. Jun, 2014 | Pubmed ID: 24724852 Resting State Functional MRI in Parkinson's Disease: the Impact of Deep Brain Stimulation on 'effective' Connectivity Brain : a Journal of Neurology. Apr, 2014 | Pubmed ID: 24566670 Predictive Factors of Speech Intelligibility Following Subthalamic Nucleus Stimulation in Consecutive Patients with Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2014 | Pubmed ID: 24532491 Pallidal Stimulation for Primary Generalised Dystonia: Effect on Cognition, Mood and Quality of Life Journal of Neurology. Jan, 2014 | Pubmed ID: 24178706 The Effect of Posterior Hypothalamus Region Deep Brain Stimulation on Sleep Cephalalgia : an International Journal of Headache. Mar, 2014 | Pubmed ID: 24045569 Short and Long Term Outcome of Bilateral Pallidal Stimulation in Chorea-acanthocytosis PloS One. 2013 | Pubmed ID: 24223913 Future of Brain Stimulation: New Targets, New Indications, New Technology Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2013 | Pubmed ID: 24123327 Phase Dependent Modulation of Tremor Amplitude in Essential Tremor Through Thalamic Stimulation Brain : a Journal of Neurology. Oct, 2013 | Pubmed ID: 24038075 The Nucleus Basalis of Meynert: a New Target for Deep Brain Stimulation in Dementia? Neuroscience and Biobehavioral Reviews. Dec, 2013 | Pubmed ID: 24035740 Subthalamic Nucleus Local Field Potential Activity During the Eriksen Flanker Task Reveals a Novel Role for Theta Phase During Conflict Monitoring The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2013 | Pubmed ID: 24027276 Dopamine Agonists Rather Than Deep Brain Stimulation Cause Reflection Impulsivity in Parkinson's Disease Journal of Parkinson's Disease. 2013 | Pubmed ID: 23938343 Successful Pallidal Deep Brain Stimulation in 15-year-old with Tourette Syndrome: 2-year Follow-up Journal of Neurology. Sep, 2013 | Pubmed ID: 23884714 Pallidal Stimulation for Cervical Dystonia Does Not Correct Abnormal Temporal Discrimination Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2013 | Pubmed ID: 23853089 Adaptive Deep Brain Stimulation in Advanced Parkinson Disease Annals of Neurology. Sep, 2013 | Pubmed ID: 23852650 Genotype and Phenotype in Parkinson's Disease: Lessons in Heterogeneity from Deep Brain Stimulation Movement Disorders : Official Journal of the Movement Disorder Society. Sep, 2013 | Pubmed ID: 23818421 Complementary Roles of Different Oscillatory Activities in the Subthalamic Nucleus in Coding Motor Effort in Parkinsonism Experimental Neurology. Oct, 2013 | Pubmed ID: 23778147 Critical Evaluation of the Anatomical Location of the Barrington Nucleus: Relevance for Deep Brain Stimulation Surgery of Pedunculopontine Tegmental Nucleus Neuroscience. Sep, 2013 | Pubmed ID: 23732233 Conclusions Should Be Supported by the Data Presented British Journal of Neurosurgery. Aug, 2013 | Pubmed ID: 23692068 Errors of Image Coregistration May Necessitate Intraoperative Refinement in Functional Neurosurgery Journal of Neurological Surgery. Part A, Central European Neurosurgery. Sep, 2013 | Pubmed ID: 23504669 Image-guided and Image-verified Deep Brain Stimulation Movement Disorders : Official Journal of the Movement Disorder Society. Feb, 2013 | Pubmed ID: 23390009 Strawberries on the Brain--intracranial Capillary Hemangioma: Two Case Reports and Systematic Literature Review in Children and Adults World Neurosurgery. Dec, 2013 | Pubmed ID: 23247022 The Risk of Hardware Infection in Deep Brain Stimulation Surgery is Greater at Impulse Generator Replacement Than at the Primary Procedure Stereotactic and Functional Neurosurgery. 2013 | Pubmed ID: 23207787 Frequency Specific Activity in Subthalamic Nucleus Correlates with Hand Bradykinesia in Parkinson's Disease Experimental Neurology. Feb, 2013 | Pubmed ID: 23178580 Caught Between a Disc and a Tumour: Lumbar Radiculopathy Secondary to Disc Herniation and Filum Paraganglioma Acta Neurochirurgica. Feb, 2013 | Pubmed ID: 23132372 Deep Brain Stimulation As a Treatment for Chorea-acanthocytosis Journal of Neurology. Jan, 2013 | Pubmed ID: 23086180 Subthalamic Nucleus Gamma Oscillations Mediate a Switch from Automatic to Controlled Processing: a Study of Random Number Generation in Parkinson's Disease NeuroImage. Jan, 2013 | Pubmed ID: 22960249 Therapeutic Subthalamic Nucleus Deep Brain Stimulation Reverses Cortico-thalamic Coupling During Voluntary Movements in Parkinson's Disease PloS One. 2012 | Pubmed ID: 23300524 Image-verified Deep Brain Stimulation Reduces Risk and Cost with No Apparent Impact on Efficacy Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2012 | Pubmed ID: 23032691 Subthalamic Nucleus Activity Optimizes Maximal Effort Motor Responses in Parkinson's Disease Brain : a Journal of Neurology. Sep, 2012 | Pubmed ID: 22858550 Movement-related Changes in Local and Long-range Synchronization in Parkinson's Disease Revealed by Simultaneous Magnetoencephalography and Intracranial Recordings The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2012 | Pubmed ID: 22855804 Pitfalls in Precision Stereotactic Surgery Surgical Neurology International. 2012 | Pubmed ID: 22826812 Deep Brain Stimulation: Linking Structure and Function in Awake and Anesthetized Patients Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Dec, 2012 | Pubmed ID: 22668823 Alpha Oscillations in the Pedunculopontine Nucleus Correlate with Gait Performance in Parkinsonism Brain : a Journal of Neurology. Jan, 2012 | Pubmed ID: 22232591 Confirmation of Functional Zones Within the Human Subthalamic Nucleus: Patterns of Connectivity and Sub-parcellation Using Diffusion Weighted Imaging NeuroImage. Mar, 2012 | Pubmed ID: 22173294 Deep Brain Stimulation in the Treatment of Chorea Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2012 | Pubmed ID: 21997283 Reducing Hemorrhagic Complications in Functional Neurosurgery: a Large Case Series and Systematic Literature Review Journal of Neurosurgery. Jan, 2012 | Pubmed ID: 21905798 Treatment of Dysarthria Following Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2011 | Pubmed ID: 21953693 Urinary Incontinence Following Deep Brain Stimulation of the Pedunculopontine Nucleus Acta Neurochirurgica. Dec, 2011 | Pubmed ID: 21927820 MRI-guided Subthalamic Nucleus Deep Brain Stimulation Without Microelectrode Recording: Can We Dispense with Surgery Under Local Anaesthesia? Stereotactic and Functional Neurosurgery. 2011 | Pubmed ID: 21921673 A Gamma Band Specific Role of the Subthalamic Nucleus in Switching During Verbal Fluency Tasks in Parkinson's Disease Experimental Neurology. Dec, 2011 | Pubmed ID: 21872587 Clinical Safety of Brain Magnetic Resonance Imaging with Implanted Deep Brain Stimulation Hardware: Large Case Series and Review of the Literature World Neurosurgery. Jul-Aug, 2011 | Pubmed ID: 21839969 Functional Imaging of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21674623 Deep Brain Stimulation Effects in Dystonia: Time Course of Electrophysiological Changes in Early Treatment Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21547950 Deep Brain Stimulation for Gilles De La Tourette Syndrome: a Case Series Targeting Subregions of the Globus Pallidus Internus Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21538528 Targeting of the Pedunculopontine Nucleus by an MRI-guided Approach: a Cadaver Study Journal of Neural Transmission (Vienna, Austria : 1996). Oct, 2011 | Pubmed ID: 21484277 Deep Brain Stimulation in Cluster Headache Expert Review of Neurotherapeutics. Apr, 2011 | Pubmed ID: 21469918 Skewering the Subthalamic Nucleus Via a Parietal Approach Stereotactic and Functional Neurosurgery. 2011 | Pubmed ID: 21293165 Gender Distribution of Patients with Parkinson's Disease Treated with Subthalamic Deep Brain Stimulation; a Review of the 2000-2009 Literature Parkinsonism & Related Disorders. Mar, 2011 | Pubmed ID: 21195012 An Approach to Deep Brain Stimulation for Severe Treatment-refractory Tourette Syndrome: the UK Perspective British Journal of Neurosurgery. Feb, 2011 | Pubmed ID: 21158507 Resting Oscillatory Cortico-subthalamic Connectivity in Patients with Parkinson's Disease Brain : a Journal of Neurology. Feb, 2011 | Pubmed ID: 21147836 Neuromodulation: Anatomical Precision is Neither Tedious nor Outdated Neuromodulation : Journal of the International Neuromodulation Society. Jan, 2010 | Pubmed ID: 21992769 Improving Targeting in Image-guided Frame-based Deep Brain Stimulation Neurosurgery. Dec, 2010 | Pubmed ID: 21099570 Comment on "A Systematic Review of the Efficacy of Globus Pallidus Stimulation in the Treatment of Parkinson's Disease" Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Nov, 2010 | Pubmed ID: 20739183 Minimizing Brain Shift in Stereotactic Functional Neurosurgery Neurosurgery. Sep, 2010 | Pubmed ID: 20679927 Deep Brain Stimulation Between 1947 and 1987: the Untold Story Neurosurgical Focus. Aug, 2010 | Pubmed ID: 20672911 Value of Subthalamic Nucleus Local Field Potentials Recordings in Predicting Stimulation Parameters for Deep Brain Stimulation in Parkinson's Disease Journal of Neurology, Neurosurgery, and Psychiatry. Aug, 2010 | Pubmed ID: 20466699 Patient-specific Model-based Investigation of Speech Intelligibility and Movement During Deep Brain Stimulation Stereotactic and Functional Neurosurgery. 2010 | Pubmed ID: 20460952 Deep Brain Stimulation in Cluster Headache: Hypothalamus or Midbrain Tegmentum? Current Pain and Headache Reports. Apr, 2010 | Pubmed ID: 20425205 Optimized Beamforming for Simultaneous MEG and Intracranial Local Field Potential Recordings in Deep Brain Stimulation Patients NeuroImage. May, 2010 | Pubmed ID: 20056156 The Role of Imaging in the Surgical Treatment of Movement Disorders Neuroimaging Clinics of North America. Feb, 2010 | Pubmed ID: 19959024 Giant Extradural Sacral Meningioma Acta Neurochirurgica. Mar, 2010 | Pubmed ID: 19479187 Early and Marked Benefit with GPi DBS for Lubag Syndrome Presenting with Rapidly Progressive Life-threatening Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2009 | Pubmed ID: 19514062 Avoiding the Ventricle: a Simple Step to Improve Accuracy of Anatomical Targeting During Deep Brain Stimulation Journal of Neurosurgery. Jun, 2009 | Pubmed ID: 19301961 Involvement of the Subthalamic Nucleus in Engagement with Behaviourally Relevant Stimuli The European Journal of Neuroscience. Mar, 2009 | Pubmed ID: 19226423 Method for Patient-specific Finite Element Modeling and Simulation of Deep Brain Stimulation Medical & Biological Engineering & Computing. Jan, 2009 | Pubmed ID: 18936999 Effects of Contact Location and Voltage Amplitude on Speech and Movement in Bilateral Subthalamic Nucleus Deep Brain Stimulation Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2008 | Pubmed ID: 18785648 Stereotactic Localization of the Human Pedunculopontine Nucleus: Atlas-based Coordinates and Validation of a Magnetic Resonance Imaging Protocol for Direct Localization Brain : a Journal of Neurology. Jun, 2008 | Pubmed ID: 18467343 Cortical Evoked Potentials from Pallidal Stimulation in Patients with Primary Generalized Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2008 | Pubmed ID: 18044698 The Peripeduncular Nucleus: a Novel Target for Deep Brain Stimulation? Neuroreport. Oct, 2007 | Pubmed ID: 17948606 The Peripeduncular Nucleus: a Novel Target for Deep Brain Stimulation? Neuroreport. Aug, 2007 | Pubmed ID: 17632287 The Pedunculopontine and Peripeduncular Nuclei: a Tale of Two Structures Brain : a Journal of Neurology. Jun, 2007 | Pubmed ID: 17525137 Pallidal Stimulation Modifies After-effects of Paired Associative Stimulation on Motor Cortex Excitability in Primary Generalised Dystonia Experimental Neurology. Jul, 2007 | Pubmed ID: 17498697 Commercial Flight and Patients with Intracranial Mass Lesions: a Caveat. Report of Two Cases Journal of Neurosurgery. Oct, 2006 | Pubmed ID: 17044569 Intra-operative Recordings of Local Field Potentials Can Help Localize the Subthalamic Nucleus in Parkinson's Disease Surgery Experimental Neurology. Mar, 2006 | Pubmed ID: 16403500 Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation Simon Little1, Alek Pogosyan1, Spencer Neal2, Ludvic Zrinzo2, Marwan Hariz2, Thomas Foltynie2, Patricia Limousin2, Peter Brown1 1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology JoVE 51403 Medicina
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation Simon Little1, Alek Pogosyan1, Spencer Neal2, Ludvic Zrinzo2, Marwan Hariz2, Thomas Foltynie2, Patricia Limousin2, Peter Brown1 1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology JoVE 51403 Medicina