Patricia Sancho Stem Cells & Cancer Group, Molecular Pathology Program Spanish National Cancer Research Center Biography Publications Institution JoVE Articles Patricia Sancho has not added a biography. If you are Patricia Sancho and would like to personalize this page please email our Author Liaison for assistance. Publications Microenvironmental HCAP-18/LL-37 Promotes Pancreatic Ductal Adenocarcinoma by Activating Its Cancer Stem Cell Compartment Gut. Apr, 2015 | Pubmed ID: 25841238 A Mesenchymal-like Phenotype and Expression of CD44 Predict Lack of Apoptotic Response to Sorafenib in Liver Tumor Cells International Journal of Cancer. Journal International Du Cancer. Feb, 2015 | Pubmed ID: 25053293 Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer Via Gata6-Dependent Dedifferentiation of Acinar Cells in Mice Gastroenterology. Nov, 2014 | Pubmed ID: 25127677 The NADPH Oxidase NOX4 Inhibits Hepatocyte Proliferation and Liver Cancer Progression Free Radical Biology & Medicine. Apr, 2014 | Pubmed ID: 24509161 [Cost-consequence Analysis of Respiratory Preventive Intervention Among Institutionalized Older People: Randomized Controlled Trial] Revista Española De Geriatría Y Gerontología. Sep-Oct, 2014 | Pubmed ID: 24417971 TGF-beta Signaling in Cancer Treatment Current Pharmaceutical Design. 2014 | Pubmed ID: 23944366 Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells PloS One. 2013 | Pubmed ID: 24204632 Overactivation of the TGF-β Pathway Confers a Mesenchymal-like Phenotype and CXCR4-dependent Migratory Properties to Liver Tumor Cells Hepatology (Baltimore, Md.). Dec, 2013 | Pubmed ID: 23813475 ROS Production is Essential for the Apoptotic Function of E2F1 in Pheochromocytoma and Neuroblastoma Cell Lines PloS One. 2012 | Pubmed ID: 23251571 Coping Strategies: Gender Differences and Development Throughout Life Span The Spanish Journal of Psychology. Nov, 2012 | Pubmed ID: 23156917 NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death During Liver Fibrosis Development PloS One. 2012 | Pubmed ID: 23049784 Predicting Perceived Health in Angolan Elderly: the Moderator Effect of Being Oldest Old Archives of Gerontology and Geriatrics. Nov-Dec, 2012 | Pubmed ID: 22770711 Protein-tyrosine Phosphatase 1B (PTP1B) Deficiency Confers Resistance to Transforming Growth Factor-β (TGF-β)-induced Suppressor Effects in Hepatocytes The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22427664 Resilience and Coping As Predictors of General Well-being in the Elderly: a Structural Equation Modeling Approach Aging & Mental Health. 2012 | Pubmed ID: 22292552 Lack of Amino Acids in Mouse Hepatocytes in Culture Induces the Selection of Preneoplastic Cells Cellular Signalling. Jan, 2012 | Pubmed ID: 21964063 Sorafenib Sensitizes Hepatocellular Carcinoma Cells to Physiological Apoptotic Stimuli Journal of Cellular Physiology. Apr, 2012 | Pubmed ID: 21604268 Reciprocal Regulation of NADPH Oxidases and the Cyclooxygenase-2 Pathway Free Radical Biology & Medicine. Nov, 2011 | Pubmed ID: 21907277 The Tyrphostin AG1478 Inhibits Proliferation and Induces Death of Liver Tumor Cells Through EGF Receptor-dependent and Independent Mechanisms Biochemical Pharmacology. Dec, 2011 | Pubmed ID: 21864510 The NADPH Oxidase Inhibitor VAS2870 Impairs Cell Growth and Enhances TGF-β-induced Apoptosis of Liver Tumor Cells Biochemical Pharmacology. Apr, 2011 | Pubmed ID: 21276422 Dissecting the Effect of Targeting the Epidermal Growth Factor Receptor on TGF-β-induced-apoptosis in Human Hepatocellular Carcinoma Cells Journal of Hepatology. Aug, 2011 | Pubmed ID: 21147185 Snail1 Suppresses TGF-beta-induced Apoptosis and is Sufficient to Trigger EMT in Hepatocytes Journal of Cell Science. Oct, 2010 | Pubmed ID: 20930141 NADPH Oxidase NOX1 Controls Autocrine Growth of Liver Tumor Cells Through Up-regulation of the Epidermal Growth Factor Receptor Pathway The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20525691 Overactivation of the MEK/ERK Pathway in Liver Tumor Cells Confers Resistance to TGF-{beta}-induced Cell Death Through Impairing Up-regulation of the NADPH Oxidase NOX4 Cancer Research. Oct, 2009 | Pubmed ID: 19773433 Role of CXCR4/SDF-1 Alpha in the Migratory Phenotype of Hepatoma Cells That Have Undergone Epithelial-mesenchymal Transition in Response to the Transforming Growth Factor-beta Cellular Signalling. Nov, 2009 | Pubmed ID: 19586611 Caspase-independent Type III Programmed Cell Death in Chronic Lymphocytic Leukemia: the Key Role of the F-actin Cytoskeleton Haematologica. Apr, 2009 | Pubmed ID: 19278964 The Inhibition of the Epidermal Growth Factor (EGF) Pathway Enhances TGF-beta-induced Apoptosis in Rat Hepatoma Cells Through Inducing Oxidative Stress Coincident with a Change in the Expression Pattern of the NADPH Oxidases (NOX) Isoforms Biochimica Et Biophysica Acta. Feb, 2009 | Pubmed ID: 18848961 Upregulation of the NADPH Oxidase NOX4 by TGF-beta in Hepatocytes is Required for Its Pro-apoptotic Activity Journal of Hepatology. Dec, 2008 | Pubmed ID: 18845355 Inhibition of the EGF Receptor Blocks Autocrine Growth and Increases the Cytotoxic Effects of Doxorubicin in Rat Hepatoma Cells: Role of Reactive Oxygen Species Production and Glutathione Depletion Biochemical Pharmacology. May, 2008 | Pubmed ID: 18371937 Drp1 Mediates Caspase-independent Type III Cell Death in Normal and Leukemic Cells Molecular and Cellular Biology. Oct, 2007 | Pubmed ID: 17682056 Pharmacological Inhibitors of Extracellular Signal-regulated Protein Kinases Attenuate the Apoptotic Action of Cisplatin in Human Myeloid Leukemia Cells Via Glutathione-independent Reduction in Intracellular Drug Accumulation Biochimica Et Biophysica Acta. Apr, 2005 | Pubmed ID: 15843040 Pharmacologic Inhibitors of PI3K/Akt Potentiate the Apoptotic Action of the Antileukemic Drug Arsenic Trioxide Via Glutathione Depletion and Increased Peroxide Accumulation in Myeloid Leukemia Cells Blood. May, 2005 | Pubmed ID: 15665116 12-O-tetradecanoylphorbol-13-acetate May Both Potentiate and Decrease the Generation of Apoptosis by the Antileukemic Agent Arsenic Trioxide in Human Promonocytic Cells. Regulation by Extracellular Signal-regulated Protein Kinases and Glutathione The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14610070 Differential Effects of Catalase on Apoptosis Induction in Human Promonocytic Cells. Relationships with Heat-shock Protein Expression Molecular Pharmacology. Mar, 2003 | Pubmed ID: 12606765 Studeren alvleesklier- Stamcel Kenmerken voor het ontwikkelen van nieuwe behandelingsstrategieën Enza Lonardo1,2, Michele Cioffi1, Patricia Sancho1,3, Shanthini Crusz3, Christopher Heeschen1,3 1Stem Cells & Cancer Group, Molecular Pathology Program, Spanish National Cancer Research Center, 2Institute for Research in Biomedicine (IRB Barcelona), 3Center for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London Medicina
Studeren alvleesklier- Stamcel Kenmerken voor het ontwikkelen van nieuwe behandelingsstrategieën Enza Lonardo1,2, Michele Cioffi1, Patricia Sancho1,3, Shanthini Crusz3, Christopher Heeschen1,3 1Stem Cells & Cancer Group, Molecular Pathology Program, Spanish National Cancer Research Center, 2Institute for Research in Biomedicine (IRB Barcelona), 3Center for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London Medicina