Materials
Name | Company | Catalog Number | Comments |
1% Tropicamide (Mydriacyl) | Alcon Inc Laboratories | Mydriatic agent | |
2% Methocel | OmniVision Eye Care | Hydroxypropryl methylcellulose gel | |
C57BL/6J | Jackson Laboratory | 000664 | Wild type mice |
Excel for Microsoft 365 | Microsoft Inc | Software package | |
Fluorescein sodium salt | Sigma-Aldrich | 28803-100G | Fluorescent angiography |
Matlab 8.0 | The MathWorks, Inc. | Software package | |
Micron IV rodent fundus camera | Phoenix-Micron | 40-2200 | Fundus photography |
Phenylephrine 10% w/v | Bausch & Lomb | Mydriatic agent | |
Phosphate Buffered Saline - 100 tablets | Gibco | 18912-014 | Dilution |
Sigmaplot 13 | Jandel Scientific Software | Software package | |
S-Ketamine, 25 mg/mL | Pfizer Inc. | PAA104470 | Anesthesia IP |
References
- Cheung, C. Y., Ikram, M. K., Chen, C., Wong, T. Y. Imaging retina to study dementia and stroke. Progress in Retinal and Eye Research. 57, 89-107 (2017).
- Selvam, S., Kumar, T., Fruttiger, M. Retinal vasculature development in health and disease. Progress in Retinal and Eye Research. 63, 1-19 (2018).
- Ma, Y., et al. Quantitative analysis of retinal vessel attenuation in eyes with retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 53 (7), 4306-4314 (2012).
- Eysteinsson, T., Hardarson, S. H., Bragason, D., Stefansson, E. Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosa. Acta Ophthalmologica. 92 (5), 449-453 (2014).
- Al-Latayfeh, M., Silva, P. S., Sun, J. K., Aiello, L. P. Antiangiogenic therapy for ischemic retinopathies. Cold Spring Harbor Perspectives in Medicine. 2 (6), 006411 (2012).
- Wang, S., Villegas-Perez, M. P., Vidal-Sanz, M., Lund, R. D. Progressive optic axon dystrophy and vacuslar changes in rd mice. Investigative Ophthalmology & Visual Science. 41 (2), 537-545 (2000).
- Liu, H., et al. Photoreceptor cells influence retinal vascular degeneration in mouse models of retinal degeneration and diabetes. Investigative Ophthalmology & Visual Science. 57 (10), 4272-4281 (2016).
- Steingrimsson, E., Copeland, N. G., Jenkins, N. A. Melanocytes and the microphthalmia transcription factor network. Annual Review of Genetics. 38, 365-411 (2004).
- Arnheiter, H. The discovery of the microphthalmia locus and its gene. Mitf. Pigment Cell & Melanoma Research. 23 (6), 729-735 (2010).
- Garcia-Llorca, A., Aspelund, S. G., Ogmundsdottir, M. H., Steingrimsson, E., Eysteinsson, T. The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function. Scientific Reports. 9 (1), 15386 (2019).
- Bharti, K., Liu, W., Csermely, T., Bertuzzi, S., Arnheiter, H. Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF. Development. 135 (6), 1169-1178 (2008).
- Lu, S. Y., Li, M., Lin, Y. L. Mitf induction by RANKL is critical for osteoclastogenesis. Molecular Biology of the Cell. 21 (10), 1763-1771 (2010).
- Pillaiyar, T., Manickam, M., Jung, S. H. Recent development of signaling pathways inhibitors of melanogenesis. Cellular Signalling. 40, 99-115 (2017).
- Danielsson, S. B., Garcia-Llorca, A., Reynisson, H., Eysteinsson, T. Mouse microphthalmia-associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature. Acta Ophthalmologica. 100 (8), 911-918 (2022).
- Burns, S. A., Elsner, A. E., Gast, T. J.
Imaging the retinal vasculature. Annual Review of Vision Science. 7, 129-153 (2021). - Wei, W., et al. Automated vessel diameter quantification and vessel tracing for OCT angiography. Journal of Biophotonics. 13 (12), e202000248 (2020).
- Salas, M., et al. Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye. Biomedical Optics Express. 9 (4), 1871-1892 (2018).
- Albanna, W., et al. Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis. PLoS One. 13 (10), e0204689 (2018).
- Moult, E. M., et al. Evaluating anesthetic protocols for functional blood flow imaging in the rat eye. Journal of Biomedical Optics. 22 (1), 16005 (2017).