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DNA vector-gebaseerde RNA-interferentie op genfunctie in Cancer Study
 
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DNA vector-gebaseerde RNA-interferentie op genfunctie in Cancer Study

Article DOI: 10.3791/4129-v • 13:10 min • June 4th, 2012
June 4th, 2012 •
1, 1, 1, 2, 1
1Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, 2Department of Pathology and Comprehensive Cancer Center, Wake Forest University School of Medicine

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RNA-interferentie (RNAi) beschikt over een groot aantal voordelen ten opzichte van gen knock-out en is in brede kring gebruikt als een instrument in gen functionele studies. De uitvinding van DNA-vector-gebaseerde RNAi-technologie heeft op lange termijn en induceerbaar gen knockdown mogelijk, en verhoogde ook de haalbaarheid van gene silencing

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Kankerbiologie geneeskunde genetica RNAi shRNA gene silencing muis xenograft tumorvorming
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