Waiting
Processando Login

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Intravital Microscopy and Thrombus Induction in…
JoVE Journal
Medicine

É necessário ter uma assinatura JoVE para assistir este Faça login ou comece sua avaliação gratuita.

JoVE Journal Medicine
Intravital Microscopy and Thrombus Induction in the Earlobe of a Hairless Mouse
 

Intravital Microscopy and Thrombus Induction in the Earlobe of a Hairless Mouse

Article DOI: 10.3791/55174-v • 09:01 min • April 2nd, 2017
April 2nd, 2017 •
*1, *2, 2, 1, 3
1Department of Otorhinolaryngology, Head and Neck Surgery "Otto Koerner", Rostock University Medical Center, 2Department of General, Thoracic, Vascular and Transplantation Surgery, Rostock University Medical Center, 3Institute for Experimental Surgery, Rostock University Medical Center
* These authors contributed equally

Capítulos

Resumo
Automatic Translation

The ear model of the hairless SKH1-Hrhr mouse enables intravital fluorescence microscopy of microcirculation and phototoxic thrombus induction without prior surgical preparation in the examined microvascular bed. Therefore, the ear of the hairless mouse is an excellent in vivo model to study the complex interactions during microvascular thrombus formation, thrombus evolution, and thrombolysis.

Tags

Keywords: Intravital Microscopy Thrombus Induction Hairless Mouse Microvascular Thrombosis Antithrombotic Substances Sepsis Tissue Transplantation Phototoxic Thrombus Induction Anesthesia Dextran Jugular Vein Fluorescent Dye
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter