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Neuroscience

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JoVE Journal Neuroscience
Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
 

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Article DOI: 10.3791/58073-v • 09:06 min • January 9th, 2019
January 9th, 2019 •
1,2, 1, 2
1Hearing Systems Group, Department of Electrical Engineering, Technical University of Denmark, 2Brain and Sound Lab, Department of Biomedicine, Basel University

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Resumo
Automatic Translation

Animal models of cochlear implants can advance knowledge of the technological bases of treating permanent sensorineural hearing loss with electrical stimulation. This study presents a surgical protocol for acute deafening and cochlear implantation of an electrode array in mice as well as the functional assessment with auditory brainstem response.

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Keywords: Cochlear Implant Auditory Brainstem Response C57BL/6 Mice Deafening Cochlear Implantation Acute Deafening Functional Assessment Cochlear Implant Surgery Auditory Brain Stem Response Hearing Loss Electric Stimulation Animal Model Stapedial Artery Round Window Niche Click Stimulus AVR Threshold
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