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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
 

Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice

Article DOI: 10.3791/59200-v • 08:51 min • May 10th, 2019
May 10th, 2019 •
1,2, 1, 1, 1, 3, 4, 5, 5, 6, 1,7, 1, 1
1Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices, 2KBRwyle GmbH, 3Cognitive Neurophysiology, Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Cologne, 4Molecular and Cellular Cognition, German Center for Neurodegenerative Diseases (DZNE), 5Institute of Neurophysiology, Faculty of Medicine, University of Cologne, 6Federal Institute for Drugs and Medical Devices (BfArM), 7Thescon GmbH

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Brainstem evoked response audiometry is an important tool in clinical neurophysiology. Nowadays, brainstem evoked response audiometry is also applied in the basic science and preclinical studies involving both pharmacological and genetic animal models. Here we provide a detailed description of how auditory brainstem responses can be successfully recorded and analyzed in mice.

Tags

Keywords: Data Acquisition Auditory Brainstem Response ABR Mice Evoked Response Audiometry Click Tone-burst Electrophysiology Hearing Loss Anesthesia Calibration Stimulus Threshold Latency Amplitude
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