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Biochemistry

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JoVE Journal Biochemistry
Screening for Thermotoga Maritima membranbundne Pyrofosfatasehæmmere
 
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Screening for Thermotoga Maritima membranbundne Pyrofosfatasehæmmere

Article DOI: 10.3791/60619-v • 09:11 min • November 23rd, 2019
November 23rd, 2019 •
*1, *2, 2, 2, 2, 2, 2, 1,3
1Research Program in Molecular and Integrative Biosciences, University of Helsinki, 2Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, 3School of Biomedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds
* These authors contributed equally

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Her præsenterer vi en screeningmetode for membranbundne pyrofosfatase (fra Thermotoga Maritima) hæmmere baseret på molybdæn blå reaktion i en 96 brønd plade format.

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Biokemi membran-bundet pyrofosfatase Thermotoga Maritima inhibitor screening molybdæn blå reaktion protist sygdomme Drug design
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