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Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
 

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Article DOI: 10.3791/62403-v • 07:13 min • April 20th, 2021
April 20th, 2021 •
*1, *2, 3, 4, 3, 1
1Comparative Medicine, Pfizer Inc., 2Digital Medicine & Translational Imaging, Pfizer Inc., 3Internal Medicine Research Unit, Pfizer Inc., 4Drug Safety Research & Development, Pfizer Inc.
* These authors contributed equally

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This protocol describes the use of an enhanced ultrasound technique to non-invasively observe and quantify liver tissue changes in rodent models of nonalcoholic fatty liver disease.

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Keywords: Ultrasound Shear Wave Elastography NAFLD NASH Rat Model Non-invasive High-throughput Drug Discovery Choline Deficient High-fat Diet Anesthesia Chemical Depilation B-mode Imaging Renal Cortex Liver Parenchyma
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