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Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
 

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Article DOI: 10.3791/62933-v • 13:07 min • January 15th, 2022
January 15th, 2022 •
1, 1, 1, 2, 3, 4, 3,5,6
1School of Mechanical Engineering, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), 4Monash Cardiovascular Research Centre, 5Adelaide Medical School, University of Adelaide, 6Department of Cardiology, Central Adelaide Local Health Network

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There is a need to determine which atherosclerotic lesions will progress in the coronary vasculature to guide intervention before myocardial infarction occurs. This article outlines the biomechanical modeling of arteries from Optical Coherence Tomography using fluid-structure interaction techniques in a commercial finite element solver to help predict this progression.

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Optical Coherence Tomography Biomechanical Fluid-Structure Interaction Analysis Coronary Atherosclerosis Progression Imaging Computational Simulation Fluid Dynamics Wall Shear Stress Endothelial Cell Function Atherosclerosis Formation Patient-specific Mechanics Fluid Structure Interaction Techniques Blood Flow Artery Mechanics Cardiac Function Optical Coherence Tomography (OCT) Invasive Angiography Clinical Relevance Results Follow-up Imaging Finite Element Method Finite Volume Method ANSYS Procedure
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