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Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
 

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging

Article DOI: 10.3791/63264-v 11:07 min November 24th, 2021
November 24th, 2021

Capítulos

Resumo

A coherent Raman scattering imaging methodology to visualize and quantify pharmaceutical compounds within the skin is described. This paper describes skin tissue preparation (human and mouse) and topical formulation application, image acquisition to quantify spatiotemporal concentration profiles, and preliminary pharmacokinetic analysis to assess topical drug delivery.

Tags

Keywords: Coherent Raman Scattering Imaging Topical Drug Quantification Cutaneous Pharmacokinetics Tissue Preparation Nude Mouse Ear Skin Human Skin Subcutaneous Fat Removal Lipid Imaging Drug Quantification
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