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Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
 

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Article DOI: 10.3791/63460-v • 06:36 min • September 1st, 2022
September 1st, 2022 •
*1,2, *3, 3, 1, 1, 1,2, 3,4, 1,2,5
1Department of Electronic and Electrical Engineering, Ewha Womans University, 2Graduate Program in Smart Factory, Ewha Womans University, 3Department of Electrical and Computer Engineering, Seoul National University, 4Graduate School of Engineering Practice, Seoul National University, 5Department of Brain and Cognitive Sciences, Ewha Womans University
* These authors contributed equally

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Here, we present the fabrication method of an optrode system with optical fibers for light delivery and an electrode array for neural recording. In vivo experiments with transgenic mice expressing channelrhodopsin-2 show the feasibility of the system for simultaneous optogenetic stimulation and electrophysiological recording.

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Keywords: Optrode Optogenetic Modulation Electrical Neural Recording LED-based System Microlens Array Wireless System Optogenetics Spinal Cord Injury Epilepsy Parkinson's Disease Alzheimer's Disease Tungsten Electrodes Optical Fibers Stereotactic Frame Thermal Heating Pad Lidocaine Craniotomy Ground Screw
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