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JoVE Journal Cancer Research
Modellering van hersenmetastase door interne halsslagaderinjectie van kankercellen
 
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Modellering van hersenmetastase door interne halsslagaderinjectie van kankercellen

Article DOI: 10.3791/64216-v • 10:01 min • August 2nd, 2022
August 2nd, 2022 •
1, 2, 1, 3, 2, *1,4, *1,5
1UQ Centre for Clinical Research, The University of Queensland, 2Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, 3School of Biomedical Sciences, The University of Queensland, 4Mater Research and Mater Research Institute, The University of Queensland, 5Pathology Queensland, Royal Brisbane Women's Hospital
* These authors contributed equally

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Hersenmetastase is een oorzaak van ernstige morbiditeit en mortaliteit bij kankerpatiënten. De meeste muismodellen voor hersenmetastasen worden gecompliceerd door systemische metastasen die de analyse van mortaliteit en therapeutische interventie-uitkomsten verstoren. Hier gepresenteerd is een protocol voor interne carotisinjectie van kankercellen dat consistente intracraniale tumoren produceert met minimale systemische tumoren.

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Kankeronderzoek Nummer 186
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