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焦距脑缺血模型大鼠大脑中动脉的血管内缝合闭塞

JoVE Journal
Neuroscience
Author Produced

This content is Free Access.

JoVE Journal Neuroscience

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat

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焦距脑缺血模型大鼠大脑中动脉的血管内缝合闭塞

DOI:

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13:50 min

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February 05, 2011

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Kutluay Uluç, Amrendra Miranpuri, Gregory C. Kujoth, Erinç Aktüre, Mustafa K. Başkaya

¹Department of Neurological Surgery, School of Medicine and Public Health,University of Wisconsin-Madison

Chapters

00:05Title
01:51Presurgical Preparations
03:01MCAO Surgery
10:41Reperfusion (Suture Removal)
11:52Post-MCAO Behavior
12:52Identifying Brain Infarct by 2,3,5-Triphenyltetrazolium Chloride (TTC)

Summary

Automatic Translation

在大鼠缺血性脑损伤的手术诱导是中风的研究中被广泛使用的模型。在这里，我们展示了大脑中动脉闭塞局灶性脑缺血诱导。还显示导致心肌梗死组织学染色和磁共振成像的可视化。

Tags

Focal Cerebral Ischemia Model Endovascular Suture Occlusion Middle Cerebral Artery Rat Stroke Reproducibility Experimentally Induced Infarct Volume Animal Model Animal Husbandry Costs Cranial Circulation Middle Cerebral Artery Occlusion Recanalization Reperfusion Endovascular Suture MCAO Model Spontaneously Hypertensive Rat (SHR)Filament With Silicon Tip Coating Optimal Occlusion Period Behavioral Indicators Of Stroke T2-weighted Magnetic Resonance Images Brain Sections Staining

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