A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 01:13Introduction
- 01:44Syringe Preparation for Intraocular Injections
- 04:48Intraocular Injection Procedure: Targeting the Retina Globally
- 06:50Selectively Targeting Retinal Ganglion Cells from the Optic Nerve Stump
- 09:28RGC Targeting by Injection of the Transected Optic Nerve Stump
- 10:31Conclusion
Tags
Optic Nerve TransectionExperimental ManipulationsMammalian CNSRetinal Ganglion CellsOptic NerveAxotomizedApoptotic Neuronal Cell DeathVitreous ChamberDrug DeliveryIntraocular InjectionsViral VectorsPlasmidsSiRNAsAdeno-Associated Virus (AAV) VectorsRGCs TargetingSuperior ColliculusApoptotic Mechanisms
