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Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
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Chapters
- 00:05Title
- 01:40Collection, Storage, and Preparation of Serum and Bronchoalveolar Lavage Fluids
- 02:58Application of Serum and BAL to the Lateral-flow Device
- 04:00Recording and Interpreting LFD Results
- 05:36Results: LFD Tests of BAL Samples from Acute Myeloid Leukemia Patients
- 07:27Conclusion
A rapid and accurate point-of-care test for invasive pulmonary aspergillosis is presented. It takes advantage of lateral-flow technology using a specific monoclonal antibody that binds to an Aspergillus antigen secreted during pulmonary infections. The assay is compatible with serum and brochoalveolar lavage and represents a novel adjunct test for disease diagnosis.
Tags
Invasive Pulmonary AspergillosisHaematological MalignancyLateral-flow TechnologyDiagnostic ChallengeMicrobiologyHistopathologyEuropean Organization For Research And Treatment Of CancerNational Institute Of Allergy And Infectious Diseases Mycology Study GroupNucleic Acid-based TestsPolymerase Chain ReactionAspergillus IdentificationHyphal MorphologiesInvasive Fungal PathogensCulture-based ApproachesBiopsy SamplesPathogenesisAngio-invasion
