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في وقت واحد تسجيل الكهربية والصغرى، والحقن وكلاء المثبطة في الدماغ القوارض
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Simultaneous Electrophysiological Recording and Micro-injections of Inhibitory Agents in the Rodent Brain
DOI:

07:52 min

July 07, 2015

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Chapters

  • 00:05Title
  • 01:50Preparing the Injectrode (Recording-injection Pipette)
  • 03:15Preparing the Animal
  • 04:51Performing the Experiment
  • 07:05Results: GABA Inhibition of Multi-unit Activity in the Superior Colliculus
  • 07:27Conclusion

Summary

Automatic Translation

Here, we craft a glass pipette with dual functions: inhibition of deep brain structures by microinjections of drugs and real-time monitoring of their effects through simultaneous electrophysiological recordings.

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