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Journal
/
Bioengineering
/
可注射药物加载超分子凝胶局部导管注入猪心
JoVE Journal
Bioengineering
This content is Free Access.
JoVE Journal
Bioengineering
An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Please note that all translations are automatically generated.
Click here for the English version.
可注射药物加载超分子凝胶局部导管注入猪心
DOI:
10.3791/52450-v
•
10:28 min
•
June 07, 2015
•
A. C. H. Pape*
1
,
Maarten H. Bakker*
1
,
Cheyenne C. S. Tseng
,
Maartje M. C. Bastings
,
Stefan Koudstaal
,
Pierfrancesco Agostoni
,
Steven A. J. Chamuleau
,
Patricia Y. W. Dankers
1
Institute for Complex Molecular Systems, Department of Biomedical Engineering, Laboratory of Chemical Biology
,
Eindhoven University of Technology
,
2
Department of Cardiology, Division Heart and Lungs, Interuniversity Cardiology Institute of the Netherlands (ICIN)
,
University Medical Center Utrecht
Chapters
00:05
Title
02:11
Formulation of the Hydrogel
03:10
Erosion and Release Experiments
04:18
Electromechanical Mapping
06:19
Intramyocardial Injection
07:53
In Vitro Drug Release
08:28
In Vitro
Endomyocardial Mapping
09:25
Conclusion
Summary
Automatic Translation
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Automatic Translation
基于脲基嘧啶酮的水凝胶超分子允许完全控制宏观凝胶特性和使用pH值溶胶 - 凝胶开关行为。在这里,我们提出了一个协议,通过直接局部递送相关领域中的猪心脏的导管输送系统制定和注射这种超分子水凝胶。
Tags
Supramolecular Hydrogel
Injectable Hydrogel
Catheter Injection
Myocardial Regeneration
Drug Delivery
Growth Factors
Exosomes
3D Electromechanical Mapping
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