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Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
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Neuroscience
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JoVE Journal Neuroscience
Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion

DOI:
10.3791/53331-v

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09:14 min

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April 05, 2016

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, , , , ,
1Molecular Neurobiology Laboratory, Department of Neurology,Heinrich-Heine-University Medical Center, 2Institute of Microsystems Technology,Hamburg University of Technology, 3Biomechanical Laboratory,BG Trauma Center Hamburg

Chapters

  • 00:05Title
  • 00:49Spinal Cord Preparation
  • 02:10Mechanical Microconnector System (mMS) Implantation
  • 04:27PEG 600 Implantation
  • 06:34Results: Representative mMS and PEG 600 Implantation Data
  • 08:09Conclusion

Summary

Automatic Translation

Automatic Translation

Severe spinal cord injuries often result in tissue defects. Two possibilities are described to successfully bridge such gaps to promote tissue adaptation, regenerative responses and functional improvement in rats via implantation of a mechanical microconnector system after acute injury and five weeks after complete spinal cord transection.

Tags

Keywords: ZeoliteADOR MethodIPC-4IPC-2Germanium-UTLHydrolysisIPC-1PPowder X-ray Diffraction

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