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تطوير التهاب القولون نموذج مدفوعة مستضد لدراسة عرض المستضدات التي كتبها مستضد الخلايا إلى خلايا T
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Chapters
- 00:05Title
- 01:28Colonic Lamina propria Cell Isolation
- 03:58Results: Host CX3CR1+ Macrophages Communicate with Donor OT-II Cells During OVA-driven Transfer Colitis
- 06:03Conclusion
In this antigen-driven colitis model, OT-II CD4+ T cells expressing a red fluorescent protein were adoptively transferred into RAG-/- mice that express a green fluorescent protein in mononuclear phagocytes (MPs). The hosts were challenged with Escherichia coli (E.coli) expressing the ovalbumin protein (OVA) fused to a cyan fluorescent protein (CFP).
