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Developmental Biology

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JoVE Journal Developmental Biology
Using Touch-evoked Response and Locomotion Assays to Assess Muscle Performance and Function in Zebrafish
 

Using Touch-evoked Response and Locomotion Assays to Assess Muscle Performance and Function in Zebrafish

Article DOI: 10.3791/54431-v • 09:40 min • October 31st, 2016
October 31st, 2016 •
*1, *1, 1, 1
1School of Biological Sciences, Monash University
* These authors contributed equally

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Summary
Automatic Translation

Zebrafish are an excellent model to study muscle function and disease. During early embryogenesis zebrafish begin regular muscle contractions producing rhythmic swimming behavior, which is altered when the muscle is disrupted. Here we describe a touch-evoked response and locomotion assay to examine swimming performance as a measure of muscle function.

Tags

Keywords: Zebrafish Muscle Performance Touch-evoked Response Locomotion Assay Neuromuscular Research High-throughput Video Recording Mechanosensory Stimulus Swimming Behavior Maximum Acceleration
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