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Measuring the Effect of Chemicals on the Growth and Reproduction of Caenorhabditis elegans
JoVE Journal
Medicine
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JoVE Journal Medicine
Measuring the Effect of Chemicals on the Growth and Reproduction of Caenorhabditis elegans
DOI:

08:12 min

October 05, 2017

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Chapters

  • 00:05Title
  • 00:55Preparation of NGM Plates Containing Either 1% DMSO or 750 μM Etoposide
  • 03:44Measurement of C. elegans Growth
  • 05:26C. elegans Egg Laying Assay
  • 06:18Results: C. elegans Growth and Reproduction with Etoposide Treatment
  • 07:41Conclusion

Summary

Automatic Translation

A basic protocol to evaluate the toxicity of chemicals in a model animal, Caenorhabditis elegans, is described. The method is convenient and useful for the development of pharmaceuticals as well as for the risk assessment of various environmental pollutants.

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