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1Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry,University Hospital Tübingen, 2Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich,University Tübingen, 3German Center for Diabetes Research (DZD),University Tübingen
Chapters
- 00:04Title
- 00:54Inducing Experimental Nephrotic Syndrome with Doxorubicin
- 02:24Implantation of Sustained-Release Pellets Containing Aprotinin
- 04:01Assessing Urine Serine Protease Activity
- 05:32Results: Analysis of Doxorubicin-induced Nephrotic Syndrome
- 06:48Conclusion
Hier beschrijven we de inductie van experimentele nefrotisch syndroom bij 129S1/SvImJ muizen door snelle retrobulbaire injectie van Doxorubicine. Wij behandelen ook nefrotisch muizen met aanhoudende release pellets met aprotinin remmen urine serine protease-activiteit te voorkomen retentie van natrium.
