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胎盘硫酸软骨素 A (plCSA) 靶向脂质高分子纳米粒的合成与表征
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Synthesis and Characterization of Placental Chondroitin Sulfate A (plCSA)-Targeting Lipid-Polymer Nanoparticles
DOI:

05:55 min

September 18, 2018

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Chapters

  • 00:04Title
  • 00:35Synthesis of DNPs
  • 01:34Conjugation of Peptides to DNPs
  • 02:54Fluorescence Microscopy Assessment of pICSA-Targeted Nanoparticle Uptake in Choriocarcinoma (JEG3) Cells
  • 04:18Results: Characterization and Cellular Uptake of plCSA-DNPs
  • 05:12Conclusion

Summary

Automatic Translation

在这里, 我们提出了一个协议, 以合成胎盘软骨素 a 结合肽 (plCSA BP) 共轭脂质高分子纳米粒子通过单步超声波和 bioconjugate 技术。这些微粒构成了一种新的工具, 用于靶向大多数人类肿瘤和胎盘滋养治疗癌症和胎盘疾病的治疗。

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