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Biology

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评价L-DOPA诱导的运动障碍在帕金森病单侧6-OHDA病变大鼠模型中
 
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评价L-DOPA诱导的运动障碍在帕金森病单侧6-OHDA病变大鼠模型中

Article DOI: 10.3791/62924-v 06:45 min October 4th, 2021
October 4th, 2021

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Summary

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Click here for the English version.

左旋多巴诱导的运动障碍的啮齿动物模型是确定治疗干预措施的宝贵工具,以减轻发展或减轻由于反复施用左旋多巴而出现的表现.该协议演示了如何在帕金森病的单侧6-OHDA病变大鼠模型中诱导和分析运动障碍样运动。

Tags

生物学,第176期,帕金森病,基底神经节,6-羟基多巴胺,左旋多巴诱导的运动障碍,异常的不自主运动
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