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肝细胞癌原位小鼠模型中的无创PET/MR成像
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
DOI:

07:47 min

August 31, 2022

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Chapters

  • 00:04Introduction
  • 01:06Subcutaneous Injection of Human Hepatocellular Carcinoma Cell Lines
  • 01:45Orthotopic Liver Implantation and Hepatic Artery Ligation
  • 04:00[18F] FMISO and [18F] FDG Injection
  • 04:42PET/MR Acquisition
  • 05:57Results: Effect of Hepatic Artery Ligation on Orthotopic Hepatocellular Carcinoma in Mice
  • 07:02Conclusion

Summary

Automatic Translation

在这里,我们提出了一种方案来创建有和没有肝动脉结扎的原位肝细胞癌异种移植物,并使用[18 F]氟咪唑([18 F]FMISO)和[18 F]氟脱氧葡萄糖([18F]FDG)对肿瘤缺氧进行非侵入性正电子发射断层扫描(PET)成像。

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