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Cyclic Mechanical Loading for Inducing Tendinopathy in Rat Achilles Tendon

March 1st, 2024
1,2, 1,2, 1, 1, 1, 1,3, 1,3, 1,2,3,4
1Musculoskeletal Translational Innovation Initiative, Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 2Mechanical Engineering Department, Boston University, 3Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 4Department of Orthopaedic Surgery, Yerevan State Medical University

Summary
Automatic Translation

Denne protokollen presenterer et testsystem som brukes til å indusere kvantifiserbare og kontrollerte utmattingsskader i en akillessene hos rotter for en in vivo-modell av overforbruksindusert tendinopati. Prosedyren består i å feste rottens ankel til en leddaktuator som utfører passiv ankeldorsifleksjon med et spesialskrevet MATLAB-skript.

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