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Journal / Biochemistry / Huellas dactilares cardiolipina en leucocitos por …
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Biochemistry

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JoVE Journal Biochemistry
Huellas dactilares cardiolipina en leucocitos por espectrometría de masas para un diagnóstico rápido del síndrome de Barth
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Huellas dactilares cardiolipina en leucocitos por espectrometría de masas para un diagnóstico rápido del síndrome de Barth

Article DOI: 10.3791/63552-v • 06:48 min • March 23rd, 2022
March 23rd, 2022 •
*1, *2, 2, 2
1Medical School, Swansea University, 2Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro
* These authors contributed equally

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Este protocolo muestra cómo obtener una "huella digital" espectrométrica de masas de cardiolipina leucocitaria para el diagnóstico del síndrome de Barth. La evaluación de la relación monolisocardiolipina a cardiolipina elevada discrimina a los pacientes con síndrome de Barth de los pacientes con insuficiencia cardíaca de control con 100% de sensibilidad y especificidad.

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Bioquímica Número 181
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