Jin-Young Lee Department of Pharmacy, College of Pharmacy Seoul National University Biography Publications Institution JoVE Articles Jin-Young Lee has not added a biography. If you are Jin-Young Lee and would like to personalize this page please email our Author Liaison for assistance. Publications Single-Factor SOX2 Mediates Direct Neural Reprogramming of Human Mesenchymal Stem Cells Via Transfection of In Vitro Transcribed MRNA Cell Transplantation. Jan, 2018 | Pubmed ID: 29909688 MIS416 Enhances Therapeutic Functions of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Against Experimental Colitis by Modulating Systemic Immune Milieu Frontiers in Immunology. 2018 | Pubmed ID: 29892282 GATA4-dependent Regulation of the Secretory Phenotype Via MCP-1 Underlies Lamin A-mediated Human Mesenchymal Stem Cell Aging Experimental & Molecular Medicine. May, 2018 | Pubmed ID: 29760459 Donor-dependent Variation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Response to Hypoxic Preconditioning and Amelioration of Limb Ischemia Experimental & Molecular Medicine. Apr, 2018 | Pubmed ID: 29674661 Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death Frontiers in Pharmacology. 2018 | Pubmed ID: 29545747 Association Between Optic Disc Hemorrhage and Renal Function in South Korea Journal of Glaucoma. Mar, 2018 | Pubmed ID: 29303881 Cytostatic Hydroxycoumarin OT52 Induces ER/Golgi Stress and STAT3 Inhibition Triggering Non-canonical Cell Death and Synergy with BH3 Mimetics in Lung Cancer Cancer Letters. Mar, 2018 | Pubmed ID: 29247826 The Dialkyl Resorcinol Stemphol Disrupts Calcium Homeostasis to Trigger Programmed Immunogenic Necrosis in Cancer Cancer Letters. Mar, 2018 | Pubmed ID: 29246646 Generation of Patient Specific Human Neural Stem Cells from Niemann-Pick Disease Type C Patient-derived Fibroblasts Oncotarget. Oct, 2017 | Pubmed ID: 29156730 State of Education Regarding Ultrasound-guided Interventions During Pain Fellowships in Korea: a Survey of Recent Fellows The Korean Journal of Pain. Oct, 2017 | Pubmed ID: 29123624 Tubulin-binding Anticancer Polysulfides Induce Cell Death Via Mitotic Arrest and Autophagic Interference in Colorectal Cancer Cancer Letters. 12, 2017 | Pubmed ID: 28943451 Development of Rapid and Highly Sensitive Detection of Bean Common Mosaic Necrosis Virus in Leguminous Crops Using Loop-mediated Isothermal Amplification Assay Journal of Virological Methods. 11, 2017 | Pubmed ID: 28866364 MiRNAs in Stem Cell Aging and Age-related Disease Mechanisms of Ageing and Development. Dec, 2017 | Pubmed ID: 28847486 Direct Conversion of Human Umbilical Cord Blood into Induced Neural Stem Cells with SOX2 and HMGA2 International Journal of Stem Cells. Nov, 2017 | Pubmed ID: 28844127 Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity Against Cancer Cell Lines Journal of Medicinal Chemistry. Jun, 2017 | Pubmed ID: 28475330 Korean Version of the Cough Symptom Score: Clinical Utility and Validity for Chronic Cough The Korean Journal of Internal Medicine. Sep, 2017 | Pubmed ID: 28352059 Cell Surface Nano-modulation for Non-invasive In vivo Near-IR Stem Cell Monitoring ChemMedChem. 01, 2017 | Pubmed ID: 27943553 Human Adipose Tissue-derived Mesenchymal Stem Cells Alleviate Atopic Dermatitis Via Regulation of B Lymphocyte Maturation Oncotarget. Jan, 2017 | Pubmed ID: 27888809 Cathepsin S Contributes to Microglia-mediated Olfactory Dysfunction Through the Regulation of Cx3cl1-Cx3cr1 Axis in a Niemann-Pick Disease Type C1 Model Glia. 12, 2016 | Pubmed ID: 27687148 Integrative Analysis of Mutational and Transcriptional Profiles Reveals Driver Mutations of Metastatic Breast Cancers Cell Discovery. 2016 | Pubmed ID: 27625789 BMI1 Inhibits Senescence and Enhances the Immunomodulatory Properties of Human Mesenchymal Stem Cells Via the Direct Suppression of MKP-1/DUSP1 Aging. Aug, 2016 | Pubmed ID: 27454161 PGE2 Maintains Self-renewal of Human Adult Stem Cells Via EP2-mediated Autocrine Signaling and Its Production is Regulated by Cell-to-cell Contact Scientific Reports. 05, 2016 | Pubmed ID: 27230257 Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2 Cancer Research. Jun, 2016 | Pubmed ID: 27197155 Discovery and Characterization of Isofistularin-3, a Marine Brominated Alkaloid, As a New DNA Demethylating Agent Inducing Cell Cycle Arrest and Sensitization to TRAIL in Cancer Cells Oncotarget. Apr, 2016 | Pubmed ID: 27006469 Signal Transducers and Activators of Transcription (STAT) Regulatory Networks in Marine Organisms: From Physiological Observations Towards Marine Drug Discovery Marine Drugs. Aug, 2015 | Pubmed ID: 26262624 Reliability and Validity of a Korean Version of the Leicester Cough Questionnaire Allergy, Asthma & Immunology Research. May, 2015 | Pubmed ID: 25749761 Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b Cell Reports. Jan, 2015 | Pubmed ID: 25600877 Engineering a Blood Vessel Network Module for Body-on-a-Chip Applications Journal of Laboratory Automation. Jun, 2015 | Pubmed ID: 25532526 MiR-410 Inhibition Induces RPE Differentiation of Amniotic Epithelial Stem Cells Via Overexpression of OTX2 and RPE65 Stem Cell Reviews. Jun, 2015 | Pubmed ID: 25351180 MiR-543 and MiR-590-3p Regulate Human Mesenchymal Stem Cell Aging Via Direct Targeting of AIMP3/p18 Age (Dordrecht, Netherlands). 2014 | Pubmed ID: 25465621 Promiscuous Methionyl-tRNA Synthetase Mediates Adaptive Mistranslation to Protect Cells Against Oxidative Stress Journal of Cell Science. Oct, 2014 | Pubmed ID: 25097229 A P38 MAPK-mediated Alteration of COX-2/PGE2 Regulates Immunomodulatory Properties in Human Mesenchymal Stem Cell Aging PloS One. 2014 | Pubmed ID: 25090227 Characterization of the Interaction Between Lysyl-tRNA Synthetase and Laminin Receptor by NMR FEBS Letters. Aug, 2014 | Pubmed ID: 24983501 Chemical Inhibition of Prometastatic Lysyl-tRNA Synthetase-laminin Receptor Interaction Nature Chemical Biology. Jan, 2014 | Pubmed ID: 24212136 Hormonal Regulation of Beta-catenin During Development of the Avian Oviduct and Its Expression in Epithelial Cell-derived Ovarian Carcinogenesis Molecular and Cellular Endocrinology. Jan, 2014 | Pubmed ID: 24055276 Hydrogen-atom-mediated Electrochemistry Nature Communications. 2013 | Pubmed ID: 24216572 Recrudescence Mechanisms and Gene Expression Profile of the Reproductive Tracts from Chickens During the Molting Period PloS One. 2013 | Pubmed ID: 24098561 Sex-specific Expression of CTNNB1 in the Gonadal Morphogenesis of the Chicken Reproductive Biology and Endocrinology : RB&E. Sep, 2013 | Pubmed ID: 24025394 Avian WNT4 in the Female Reproductive Tracts: Potential Role of Oviduct Development and Ovarian Carcinogenesis PloS One. 2013 | Pubmed ID: 23843947 Chemical Suppression of an Oncogenic Splicing Variant of AIMP2 Induces Tumour Regression The Biochemical Journal. Sep, 2013 | Pubmed ID: 23815603 Hypermethylation and Post-transcriptional Regulation of DNA Methyltransferases in the Ovarian Carcinomas of the Laying Hen PloS One. 2013 | Pubmed ID: 23613894 HMGA2 Regulates the in Vitro Aging and Proliferation of Human Umbilical Cord Blood-derived Stromal Cells Through the MTOR/p70S6K Signaling Pathway Stem Cell Research. Mar, 2013 | Pubmed ID: 23276696 Distinct Expression Pattern and Post-transcriptional Regulation of Cell Cycle Genes in the Glandular Epithelia of Avian Ovarian Carcinomas PloS One. 2012 | Pubmed ID: 23236518 AIMP3/p18 Controls Translational Initiation by Mediating the Delivery of Charged Initiator TRNA to Initiation Complex Journal of Molecular Biology. Nov, 2012 | Pubmed ID: 22867704 Interaction of Two Translational Components, Lysyl-tRNA Synthetase and P40/37LRP, in Plasma Membrane Promotes Laminin-dependent Cell Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2012 | Pubmed ID: 22751010 Chicken Pleiotrophin: Regulation of Tissue Specific Expression by Estrogen in the Oviduct and Distinct Expression Pattern in the Ovarian Carcinomas PloS One. 2012 | Pubmed ID: 22496782 Dual Role of Methionyl-tRNA Synthetase in the Regulation of Translation and Tumor Suppressor Activity of Aminoacyl-tRNA Synthetase-interacting Multifunctional Protein-3 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22106287 Differential Expression of Alpha 2 Macroglobulin in Response to Dietylstilbestrol and in Ovarian Carcinomas in Chickens Reproductive Biology and Endocrinology : RB&E. Oct, 2011 | Pubmed ID: 21978460 Cancer-associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis PLoS Genetics. Mar, 2011 | Pubmed ID: 21483803 Vascular Smooth Muscle Dysfunction and Remodeling Induced by Ginsenoside Rg3, a Bioactive Component of Ginseng Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2010 | Pubmed ID: 20643749 Identification of Gp96 As a Novel Target for Treatment of Autoimmune Disease in Mice PloS One. Mar, 2010 | Pubmed ID: 20352117 Bacteroides Fragilis Enterotoxin Induces Human Beta-defensin-2 Expression in Intestinal Epithelial Cells Via a Mitogen-activated Protein Kinase/I KappaB Kinase/NF-kappaB-dependent Pathway Infection and Immunity. May, 2010 | Pubmed ID: 20231411 Palmitate Induces Insulin Resistance Without Significant Intracellular Triglyceride Accumulation in HepG2 Cells Metabolism: Clinical and Experimental. Jul, 2010 | Pubmed ID: 20006364 U-shaped Dose Response in Vasomotor Tone: a Mixed Result of Heterogenic Response of Multiple Cells to Xenobiotics Toxicological Sciences : an Official Journal of the Society of Toxicology. May, 2008 | Pubmed ID: 18281258 Vacuolating Cytotoxin in Helicobacter Pylori Water-soluble Proteins Upregulates Chemokine Expression in Human Eosinophils Via Ca2+ Influx, Mitochondrial Reactive Oxygen Intermediates, and NF-kappaB Activation Infection and Immunity. Jul, 2007 | Pubmed ID: 17452475 Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts Jin-Young Lee*1, Aloran Mazumder*1, Marc Diederich1 1Department of Pharmacy, College of Pharmacy, Seoul National University JoVE 57490 Recherche en cancérologie
Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts Jin-Young Lee*1, Aloran Mazumder*1, Marc Diederich1 1Department of Pharmacy, College of Pharmacy, Seoul National University JoVE 57490 Recherche en cancérologie