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JoVE Journal Cancer Research
Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts
 

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

Article DOI: 10.3791/57490-v • 09:20 min • June 26th, 2018
June 26th, 2018 •
*1, *1, 1
1Department of Pharmacy, College of Pharmacy, Seoul National University
* These authors contributed equally

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Here, we present the preclinical screening of anticancer coumarins using 3D culture and zebrafish.

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Keywords: Preclinical Assessment Bioactivity Anticancer Coumarin OT48 Spheroids Colony Formation Assays Zebrafish Xenografts In Vitro In Vivo 3D Culture Systems A549 Cells RPMI 1640 Medium Methylcellulose-based Medium MTT Assay ImageJ Software Drug Discovery
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