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Bioengineering

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JoVE Journal Bioengineering
Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
 

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Article DOI: 10.3791/3981-v • 10:19 min • August 9th, 2012
August 9th, 2012 •
*1, *1, 2, 2, 1, 1
1Children's Hospital Boston, Harvard Medical School, 2Tufts University
* These authors contributed equally

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résumé
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Surgical stages of bladder augmentation are described using 3-D scaffolds in murine and rat models. To test the efficacy of biomaterial configurations for use in bladder augmentation, techniques for both awake and anesthetized cystometry are presented.

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Biomaterials Bladder Augmentation Cystometric Analyses Rodent Models Renal Function Continence Of Urine Urinary Bladder Low Pressure Contraction Congenital Anomalies Acquired Urological Anomalies Posterior Urethral Valves Benign Prostatic Hyperplasia Neurogenic Bladder Spina Bifida Spinal Cord Injury Pathologic Tissue Remodeling Impaired Compliance Reduced Capacity Urinary Tract Obstruction Urinary Incontinence Kidney Damage Surgical Implantation Gastrointestinal Segments Organ Capacity Expansion Intravesical Pressures Reduction Donor Tissue Limitation Complications Chronic Urinary Tract Infection Metabolic Perturbation Urinary Stone Formation Secondary Malignancy Bladder Tissue Engineering Biomaterial Configurations
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